Comparison between High Definition FT-IR, Raman and AFM-IR for subcellular chemical imaging of cholesteryl esters in prostate cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biophotonics"
DOI: 10.1002/jbio.201960094
Abstract: The family of vibrational spectroscopic imaging techniques grows every few years and there is a need to compare and contrast new modalities with the better understood ones, especially in the case of demanding biological samples.… read more here.
Keywords: chemical imaging; high definition; definition raman; chemical ... See more keywords
Effective processing and evaluation of chemical imaging data with respect to morphological features of the zebrafish embryo
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-03131-4
Abstract: A workflow was developed and implemented in a software tool for the automated combination of spatially resolved laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) data and data on the morphology of the biological tissue. Making use… read more here.
Keywords: icp data; chemical imaging; zebrafish embryo; processing evaluation ... See more keywords
Nanoscale chemical imaging of individual chemotherapeutic cytarabine-loaded liposomal nanocarriers
Sign Up to like & getrecommendations! Published in 2018 at "Nano Research"
DOI: 10.1007/s12274-018-2202-x
Abstract: Dosage of chemotherapeutic drugs is a tradeoff between efficacy and side-effects. Liposomes are nanocarriers that increase therapy efficacy and minimize side-effects by delivering otherwise difficult to administer therapeutics with improved efficiency and selectivity. Still, variabilities… read more here.
Keywords: nanoscale chemical; chemical imaging; drug; cytarabine ... See more keywords
Hyperspectral chemical imaging reveals spatially varied degradation of polycarbonate urethane (PCU) biomaterials.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.03.045
Abstract: Hyperspectral chemical imaging (HCI) is an emerging technique which combines spectroscopy with imaging. Unlike traditional point spectroscopy, which is used in the majority of polymer biomaterial degradation studies, HCI enables the acquisition of spatially localised… read more here.
Keywords: degradation; chemical imaging; hyperspectral chemical; polycarbonate urethane ... See more keywords
Fast Raman chemical imaging of tablets with non-flat surfaces.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.05.004
Abstract: A curved area with embossment on an analgesic tablet with three APIs is imaged with a Raman instrument equipped with hardware options that allow for continuous focus adjustment and very fast acquisition of micro-Raman spectra,… read more here.
Keywords: chemical imaging; non flat; tablets non; raman chemical ... See more keywords
Chemical imaging and diffusion of hydrogen and lithium in lithium aluminate
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nuclear Materials"
DOI: 10.1016/j.jnucmat.2018.08.057
Abstract: Abstract Tritium (3H) must be replenished for strategic stockpile and fusion reactors. 6Li-enriched γ-LiAlO2 pellets have been used for 3H production by thermal neutron irradiation. A fundamental study of 3H and 6Li diffusion processes in… read more here.
Keywords: lialo2 pellets; chemical imaging; diffusion; imaging diffusion ... See more keywords
Chemical imaging with Laser Ablation – Spark Discharge – Optical Emission Spectroscopy (LA-SD-OES) and Laser-Induced Breakdown Spectroscopy (LIBS)
Sign Up to like & getrecommendations! Published in 2020 at "Optics and Laser Technology"
DOI: 10.1016/j.optlastec.2019.105944
Abstract: Abstract Chemical imaging by Laser ablation – spark discharge – optical emission spectroscopy (LA-SD-OES) is presented. A low-energy laser pulse triggers an electric spark between a metal electrode tip and a sample and the excited… read more here.
Keywords: chemical imaging; laser; spark; discharge ... See more keywords
Nanoscale chemical imaging of a deuterium-labeled polyolefin copolymer in a polyolefin blend by atomic force microscopy-infrared spectroscopy
Sign Up to like & getrecommendations! Published in 2017 at "Polymer"
DOI: 10.1016/j.polymer.2017.09.045
Abstract: Abstract A combination of atomic force microscopy-infrared spectroscopy (AFM-IR) and a deuterium-labeled ethylene-propylene (EP) copolymer enables direct nanoscale chemical imaging of all three components in a polyethylene/polypropylene/ethylene-propylene copolymer blend for the first time. AFM-IR is… read more here.
Keywords: chemical imaging; microscopy; deuterium labeled; spectroscopy ... See more keywords
Tetramodal Chemical Imaging Delineates the Lipid–Amyloid Peptide Interplay at Single Plaques in Transgenic Alzheimer’s Disease Models
Sign Up to like & getrecommendations! Published in 2023 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c05302
Abstract: Beta-amyloid (Aβ) plaque pathology is one of the most prominent histopathological feature of Alzheimer’s disease (AD). The exact pathogenic mechanisms linking Aβ to AD pathogenesis remain however not fully understood. Recent advances in amyloid-targeting pharmacotherapies… read more here.
Keywords: alzheimer disease; microscopy; plaque; single plaques ... See more keywords
Multimodal Chemical Imaging of Amyloid Plaque Polymorphism Reveals Aβ Aggregation Dependent Anionic Lipid Accumulations and Metabolism.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b01361
Abstract: Amyloid plaque formation constitutes one of the main pathological hallmarks of Alzheimer's disease (AD) and is suggested to be a critical factor driving disease pathogenesis. Interestingly, in patients that display amyloid pathology but remain cognitively… read more here.
Keywords: chemical imaging; chemistry; multimodal chemical; plaque ... See more keywords
Soft X-ray Ptychography Chemical Imaging of Degradation in a Composite Surface-Reconstructed Li-Rich Cathode.
Sign Up to like & getrecommendations! Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.0c08891
Abstract: The capability in spatially resolving the interactions between components in lithium (Li)-ion battery cathodes, especially correlating chemistry and electronic structure, is challenging but critical for a better understanding of complex degradation mechanisms for rational developments.… read more here.
Keywords: degradation; chemical imaging; imaging degradation; ptychography ... See more keywords