2H-Azirines as Potential Bifunctional Chemical Linkers of Cysteine Residues in Bioconjugate Technology.
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DOI: 10.1021/acs.orglett.0c00415
Abstract: 2H-Azirine-2-caboxamides have been designed to perform as a new type of bifunctional thiol linker under very mild reaction conditions. The cleavage of a C-N double bond of 2H-azirine furnishes an amino amide functional group in… read more here.
Keywords: potential bifunctional; linkers cysteine; bifunctional chemical; chemical linkers ... See more keywords