Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp)
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DOI: 10.1002/med.21739
Abstract: Multidrug resistance (MDR) remains one of the major impediments for efficacious cancer chemotherapy. Increased efflux of multiple chemotherapeutic drugs by transmembrane ATP‐binding cassette (ABC) transporter superfamily is considered one of the primary causes for cancer… read more here.
Keywords: molecular based; chemical molecular; drug; multidrug resistance ... See more keywords
Characterisation of SnSe thin films fabricated by chemical molecular beam deposition for use in thin film solar cells
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DOI: 10.1016/j.solener.2017.11.053
Abstract: Abstract SnSe thin films were fabricated the first time by chemical molecular beam deposition (CMBD) in atmospheric pressure hydrogen flow using polycrystalline tin selenium (SnSe) precursors. The morphological and electrical properties of the films were… read more here.
Keywords: thin films; chemical molecular; snse thin; films fabricated ... See more keywords
Quantum Chemical and Molecular Dynamics Studies of MUC1 Calix[4, 8]arene Scaffold Based Anticancer Vaccine Candidates
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DOI: 10.1021/acs.jcim.9b00989
Abstract: Functional antitumor vaccine constructs are the basis for active tumor immunotherapy, which is useful in the treatment of many types of cancers. MUC1 is one key protein for targeting and designing new strategies for multi-component… read more here.
Keywords: calix arene; quantum chemical; molecular dynamics; chemical molecular ... See more keywords
Quantum chemical molecular dynamics and metadynamics simulation of aluminium binding to amyloid-β and related peptides
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DOI: 10.1098/rsos.191562
Abstract: We report semi-empirical tight-binding simulations of the interaction between Al(III) and biologically relevant peptides. The GFN2-XTB method is shown to accurately reproduce previously reported and density functional theory (DFT)-calculated geometries of model systems. Molecular dynamics… read more here.
Keywords: quantum chemical; molecular dynamics; chemical molecular; metadynamics simulation ... See more keywords
Chemical and Molecular Variations in Commercial Epoxide Photoresists for X-ray Lithography
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DOI: 10.3390/app8040528
Abstract: The quality of high aspect ratio microstructures fabricated by deep X-ray lithography is highly dependent on the photoresist material used and the process parameters applied. Even with photoresists more suitable to this process, it is… read more here.
Keywords: molecular variations; chemical molecular; ray lithography; variations commercial ... See more keywords