Chemical screening in zebrafish for novel biological and therapeutic discovery.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2016.10.004
Abstract: Zebrafish chemical screening allows for an in vivo assessment of small molecule modulation of biological processes. Compound toxicities, chemical alterations by metabolism, pharmacokinetic and pharmacodynamic properties, and modulation of cell niches can be studied with… read more here.
Keywords: therapeutic discovery; chemical screening; screening zebrafish; discovery chemical ... See more keywords
Chemical screening approach using single leaves identifies compounds that affect cold signaling in Arabidopsis.
Sign Up to like & getrecommendations! Published in 2023 at "Plant physiology"
DOI: 10.1093/plphys/kiad280
Abstract: The identification of chemical compounds that affect intracellular processes has greatly contributed to our understanding of plant growth and development. In most cases, these compounds have been identified in germinated seedlings. However, chemical screening using… read more here.
Keywords: using single; chemical screening; single leaves; compounds affect ... See more keywords
Chemical screening identifies the anticancer properties of Polyporous parvovarius
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cancer"
DOI: 10.7150/jca.78302
Abstract: One of the biggest obstacles in cancer treatment is the development of chemoresistance. To overcome this, attempts have been made to screen novel anticancer substances derived from natural products. The purpose of this study is… read more here.
Keywords: culture extract; identifies anticancer; screening identifies; anticancer ... See more keywords