PET/Fluorescence Imaging: An Overview of the Chemical Strategies to Build Dual Imaging Tools.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.1c00503
Abstract: Molecular imaging is a biomedical research discipline that has quickly emerged to afford the observation, characterization, monitoring, and quantification of biomarkers and biological processes in living organism. It covers a large array of imaging techniques,… read more here.
Keywords: overview chemical; imaging; fluorescence imaging; chemical strategies ... See more keywords
(Bio)Chemical strategies to modulate amyloid-β self-assembly.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00239
Abstract: Amyloid plaques are one of the two hallmarks of Alzheimer's disease (AD). They consist mainly of fibrils made of self-assembled amyloid-β (Aβ) peptides. Aβ is produced in healthy brains from proteolytic cleavage of the amyloid… read more here.
Keywords: modulate amyloid; self assembly; chemical strategies; self ... See more keywords
Chemical strategies to overcome resistance against targeted anticancer therapeutics
Sign Up to like & getrecommendations! Published in 2020 at "Nature Chemical Biology"
DOI: 10.1038/s41589-020-0596-8
Abstract: Emergence of resistance is a major factor limiting the efficacy of molecularly targeted anticancer drugs. Understanding the specific mutations, or other genetic or cellular changes, that confer drug resistance can help in the development of… read more here.
Keywords: overcome resistance; chemical strategies; resistance; strategies overcome ... See more keywords
Chemical Strategies towards the Development of Effective Anticancer Peptides.
Sign Up to like & getrecommendations! Published in 2023 at "Current medicinal chemistry"
DOI: 10.2174/0929867330666230426111157
Abstract: Cancer is increasingly recognized as one of the primary causes of death and has become a multifaceted global health issue. Modern medical science has made significant advancements in the diagnosis and therapy of cancer over… read more here.
Keywords: chemical strategies; towards development; anticancer peptides; strategies towards ... See more keywords