Miniaturized and Automated Synthesis of Biomolecules-Overview and Perspectives.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201806656
Abstract: Chemical synthesis is performed by reacting different chemical building blocks with defined stoichiometry, while meeting additional conditions, such as temperature and reaction time. Such a procedure is especially suited for automation and miniaturization. Life sciences… read more here.
Keywords: miniaturized automated; automated synthesis; biomolecules overview; synthesis biomolecules ... See more keywords
Size Matters: Chemical Synthesis of a Homogenous Arabinogalactan 92‐mer
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DOI: 10.1002/cbic.201700311
Abstract: 31+30+31: Ye and colleagues have synthesized a branched 92-mer of arabinogalactan-a major component of the cell wall of M. tuberculosis-by linking a linear oligogalactan 30-mer with two d-arabinofuranose 31-mers. Their approach capitalizes on sequential, one-pot glycosylation… read more here.
Keywords: synthesis homogenous; mer; matters chemical; chemical synthesis ... See more keywords
Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides cthGAMP
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200005
Abstract: The cGAS‐STING pathway is known for its role in sensing cytosolic DNA introduced by a viral infection, bacterial invasion or tumorigenesis. Free DNA is recognized by the cyclic GMP‐AMP synthase (cGAS) catalyzing the production of… read more here.
Keywords: cyclic dinucleotides; dinucleotides cthgamp; chemical synthesis; fluorescent cyclic ... See more keywords
Chemical Synthesis of Ketopentose‐5‐phosphates
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DOI: 10.1002/ejoc.201601639
Abstract: The chemical synthesis of ketopentose-5-phosphates that are involved in the pentose phosphate pathway is developed. The ketopentose phosphates, D-ribulose-5-phosphate and D-xylulose-5-phosphate, were prepared in five steps starting from known intermediates. Starting from readily available D-aldopentoses,… read more here.
Keywords: methodology; ketopentose phosphates; chemical synthesis; synthesis ketopentose ... See more keywords
Directed In Situ Shaping of Complex Nano- and Microstructures during Chemical Synthesis.
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DOI: 10.1002/marc.201600558
Abstract: Chemical composition and shape determine the basic properties of any object. Commonly, chemical synthesis and shaping follow each other in a sequence, although their combination into a single process would be an elegant simplification. Here,… read more here.
Keywords: situ shaping; directed situ; shaping complex; chemical synthesis ... See more keywords
Development of a strategy for the total chemical synthesis of an allergenic protein: the peach LTP Pru p 3
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Peptide Science"
DOI: 10.1002/psc.2981
Abstract: The possibility to obtain allergenic proteins by means of total chemical synthesis would be a big step forward in the development of cures to food allergy and in the study of the mechanism of allergic… read more here.
Keywords: total chemical; allergenic protein; synthesis allergenic; chemical synthesis ... See more keywords
Chemical synthesis of per‐selenocysteine human epidermal growth factor
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Peptide Science"
DOI: 10.1002/psc.3464
Abstract: Human seleno‐epidermal growth factor (seleno‐EGF), a 53‐residue peptide where all six cysteine residues of the parent human EGF sequence were replaced by selenocysteines, was synthesized and the oxidative folding of a polypeptide containing three diselenide… read more here.
Keywords: chemical synthesis; selenocysteine; epidermal growth; growth factor ... See more keywords
Comparative simulation study of chemical synthesis of energetic (R)‐1,2,4‐butanetriol trinitrate plasticizer
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Quantum Chemistry"
DOI: 10.1002/qua.25402
Abstract: A chemical synthesis method that involved aldol condensation and betenediol epoxidation was designed with the aid of Gaussian 09 and Materials Studio 6.0 software to accomplish simulation of the corresponding preparation processes of (R)-1,2,4-butanetriol trinitrate… read more here.
Keywords: butanetriol trinitrate; reaction; chemical synthesis; simulation ... See more keywords
Chemical synthesis of terpenoids with participation of cyclizations plus rearrangements of carbocations: a current overview
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DOI: 10.1007/s11101-019-09646-8
Abstract: Many terpenoids are biosynthesized after a cascade of cyclizations and rearrangements of carbocations mediated by terpenoid synthases, as exemplified in the biosynthesis of lanosterol. Although several reports of organisms or purified enzymes catalyzing this cascade… read more here.
Keywords: participation; rearrangements carbocations; terpenoids participation; participation cyclizations ... See more keywords
Chemical Synthesis Residual Pyrolysis and Combustion: Kinetics and Evolved Gases Investigated by TG-FTIR
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DOI: 10.1007/s11630-019-1140-6
Abstract: Chemical synthetic residual is one of the solid wastes generated from pharmaceutical industry. The pyrolysis and combustion characteristics of chemical synthesis residual were investigated using a thermogravimetric analyser coupled with Fourier transform infrared spectroscopy (TG-FTIR)… read more here.
Keywords: chemical synthesis; combustion; synthesis residual; pyrolysis ... See more keywords
Scalable, efficient and rapid chemical synthesis of l-Fructose with high purity.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate research"
DOI: 10.1016/j.carres.2019.05.010
Abstract: An improved process for chemical synthesis of l-fructose with high purity in large scale from readily available l-sorbose is described. In general, this synthetic scheme is characterized by inexpensive and easily available starting materials, simple… read more here.
Keywords: fructose high; purity; chemical synthesis; high purity ... See more keywords