Selective chemical tracking of Dnmt1 catalytic activity in live cells
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DOI: 10.1016/j.molcel.2022.02.008
Abstract: Summary Enzymatic methylation of cytosine to 5-methylcytosine in DNA is a fundamental epigenetic mechanism involved in mammalian development and disease. DNA methylation is brought about by collective action of three AdoMet-dependent DNA methyltransferases, whose catalytic… read more here.
Keywords: dna; dnmt1 catalytic; chemical tracking; selective chemical ... See more keywords