Production of chemicals using dynamic control of metabolic fluxes.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2017.10.009
Abstract: Engineered microbial cell factories are constantly experiencing metabolic imbalance due to nutrients depletion, metabolites buildup, evolutionary pressure or genetic instability. It is important to equip the engineered cell factory with sensor-regulator system to enable cell… read more here.
Keywords: dynamic control; production chemicals; control; using dynamic ... See more keywords
Mode of Action Assignment of Chemicals Using Toxicogenomics: A Case Study with Oxidative Uncouplers
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Environmental Science"
DOI: 10.3389/fenvs.2017.00080
Abstract: A criterion frequently used to group chemicals in risk assessment is “mode of toxic action” (MoA). Routinely, structure-based approaches are used for the MoA categorization of chemicals, but they can produce conflicting results or fail… read more here.
Keywords: toxicogenomic profiles; based approaches; structure based; mode action ... See more keywords