Physiologically Based Pharmacokinetic Models Predicting Renal and Hepatic Concentrations of Industrial Chemicals after Virtual Oral Doses in Rats.
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DOI: 10.1021/acs.chemrestox.0c00009
Abstract: Recently developed high-throughput in vitro assays in combination with computational models could provide alternatives to animal testing. The purpose of the present study was to model the plasma, hepatic, and renal pharmacokinetics of approximately 150… read more here.
Keywords: based pharmacokinetic; renal hepatic; physiologically based; industrial chemicals ... See more keywords