LAUSR

Cheminformatics Modeling of Gene Silencing for Both Natural and Chemically Modified siRNAs

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1 Published in 2022 at "Molecules"

DOI: 10.3390/molecules27196412

Abstract: In designing effective siRNAs for a specific mRNA target, it is critically important to have predictive models for the potency of siRNAs. None of the published methods characterized the chemical structures of individual nucleotides constituting… read more here.

Keywords: cheminformatics modeling; chemically modified; gene silencing; natural chemically ... See more keywords