Chemistries of bifunctional PROTAC degraders.
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DOI: 10.1039/d2cs00220e
Abstract: Proteolysis targeting chimeras (PROTACs) technology is a novel and promising therapeutic strategy using small molecules to induce ubiquitin-dependent degradation of proteins. It has received extensive attention from both academia and industry as it can potentially… read more here.
Keywords: development; chemistries bifunctional; protac degraders; optimization ... See more keywords