Applications of covalent chemistry in targeted protein degradation.
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DOI: 10.1039/d2cs00362g
Abstract: Proteolysis-targeting chimeras (PROTACs) and targeted covalent inhibitors (TCIs) are currently two exciting strategies in the fields of chemical biology and drug discovery. Extensive research in these two fields has been conducted, and significant progress in… read more here.
Keywords: applications covalent; chemistry; targeted protein; chemistry targeted ... See more keywords