Relapses and outcomes of systemic chemo-free therapies combined with intravitreous methotrexate in isolated primary vitreoretinal lymphoma: an analysis based on two prospective cohort studies
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DOI: 10.1007/s00277-025-06414-x
Abstract: The definitive therapeutic paradigm for primary vitreoretinal lymphoma (PVRL) remains controversial, with ongoing debates surrounding the comparative efficacy of localized ocular therapy, high-dose systemic chemotherapy, and combined-modality approaches. The benefit of systemic administration of methotrexate… read more here.
Keywords: vitreoretinal lymphoma; chemo free; systemic chemo; primary vitreoretinal ... See more keywords
Towards a chemo‐free approach for follicular lymphoma
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DOI: 10.1111/bjh.70126
Abstract: The therapeutic landscape of follicular lymphoma (FL) is undergoing a transformative shift driven by the advent of novel chemo‐free strategies that challenge the traditional chemo‐oriented paradigms; this shift offers promising alternatives for both newly diagnosed… read more here.
Keywords: follicular lymphoma; chemo free; free approach; therapy ... See more keywords
Abstract P3-11-13: Efficacy and Safety of Chemo-Free Regimens in HER2-Positive Early Breast Cancer: A Comprehensive Systematic Review and Meta-Analysis
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DOI: 10.1158/1557-3265.sabcs24-p3-11-13
Abstract: Background: Human epidermal growth factor receptor-2 (HER2)-positive breast cancer is a rapidly growing cancer that has poor outcomes if left untreated. Generally, this cancer requires treatment with aggressive chemotherapy and HER2-targeting therapies. However, there is… read more here.
Keywords: cancer; breast cancer; free regimens; her2 positive ... See more keywords
Chemo-free regimen based on venetoclax and azacytidine as induction therapy for adults with newly-diagnosed mixed phenotype acute leukemia
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DOI: 10.1182/blood-2025-6904
Abstract: Introduction Mixed phenotype acute leukemia (MPAL) is a rare type of leukemia with a poor prognosis and lack of standard treatment. Venetoclax (ven) plus azacitidine (aza) has been the standard care for patients with newly-diagnosed… read more here.
Keywords: newly diagnosed; leukemia; free regimen; acute ... See more keywords
Primary Testicular Lymphoma with Central Nervous System Relapse Was Successfully Treated by a Chemo-Free Regimen: A Case Report and Literature Review
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DOI: 10.2147/cmar.s341342
Abstract: Abstract Primary testicular lymphoma (PTL) is a rare malignancy of testis. Although the multimodality treatment (including orchiectomy, systemic chemotherapy, scrotal radiotherapy, and preventive central nervous system (CNS)-targeted treatment) is widely used to treat PTL, recurrence,… read more here.
Keywords: free regimen; chemo free; treatment; case ... See more keywords
Photoresponsive 'chemo-free' phytotherapy: formulation development for the treatment of triple-negative breast cancer.
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DOI: 10.2217/nnm-2023-0231
Abstract: Aim: The present investigation aimed to develop a chemo-free, nanophytosomal system to treat triple-negative breast cancer (TNBC) via a phyto-photo dual treatment strategy. Method: Size, shape, surface analysis, photoprovoked release profile, photothermal stability, (3-(4, 5-dimethylthiazolyl-2)-2,… read more here.
Keywords: breast cancer; treatment; negative breast; triple negative ... See more keywords
Chemo-free maintenance therapy in adult T-cell acute lymphoblastic leukemia: A case report and literature review
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DOI: 10.3389/fphar.2023.1051305
Abstract: Maintenance therapy in adult T-cell acute lymphoblastic leukemia (T-ALL) is the longest phase but with limited option. The classic drugs used in the maintenance phase such as 6-mercaptopurine, methotrexate, corticosteroid and vincristine have potentially serious… read more here.
Keywords: cell; maintenance; free maintenance; chemo free ... See more keywords