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   Articles with "chemo immunotherapy" as a keyword



pH/Cathepsin B Hierarchical‐Responsive Nanoconjugates for Enhanced Tumor Penetration and Chemo‐Immunotherapy

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recommendations! Published in 2020 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202003757

Abstract: An ideal cancer nanomedicine should precisely deliver therapeutics to its intracellular target within tumor cells. However, the multiple biological barriers seriously hinder their delivery efficiency, leading to unsatisfactory therapeutic outcome. Herein, pH/cathepsin B hierarchical‐responsive nanoconjugates… read more here.

Keywords: tumor; chemo immunotherapy; cathepsin hierarchical; responsive nanoconjugates ... See more keywords

Self‐Carrier Nanoparticles for Delivery of Paclitaxel and IDO Inhibitor to Boost Antitumor Chemo‐Immunotherapy

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202312500

Abstract: The combination of chemotherapy and immunotherapy holds great potential in clinical treatment of advanced cancers. Whereas, the therapeutic outcome of chemotherapeutic and immune regulator is suboptimal due to their poor tumor availability and severe off‐target… read more here.

Keywords: chemo immunotherapy; self carrier; carrier nanoparticles; immunotherapy ... See more keywords

Retrospective analysis on R‐DHAP/OX and ASCT as salvage treatment for relapsed/refractory high‐risk follicular lymphoma

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recommendations! Published in 2017 at "Hematological Oncology"

DOI: 10.1002/hon.2439_119

Abstract: The outcome of patients with follicular lymphoma (FL) experiencing disease progression within the first two years from first-line chemo-immunotherapy is poor and optimal subsequent management is uncertain. The combination of rituximab, dexamethasone, high-dose cytarabine, and… read more here.

Keywords: dhap; line; first line; chemo immunotherapy ... See more keywords
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Reinforcing the Induction of Immunogenic Cell Death Via Artificial Engineered Cascade Bioreactor-Enhanced Chemo-Immunotherapy for Optimizing Cancer Immunotherapy.

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recommendations! Published in 2021 at "Small"

DOI: 10.1002/smll.202101897

Abstract: Traditional chemo-immunotherapy can elicit T cell immune response by inducing immunogenic cell death (ICD), however, insufficient ICD limits the lasting antitumor immunotherapeutic efficacy. Herein, tadpole-ovoid manganese-doped hollow mesoporous silica coated gold nanoparticles (Au@HMnMSNs) as biodegradable… read more here.

Keywords: immunogenic cell; immunotherapy; chemo immunotherapy; cascade ... See more keywords

A Three‐in‐One Nanoscale Coordination Polymer for Potent Chemo‐Immunotherapy

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recommendations! Published in 2023 at "Small Methods"

DOI: 10.1002/smtd.202201437

Abstract: The addition of immune checkpoint blockade to standard chemotherapy has changed the standards of care for some cancer patients. However, current chemo‐immunotherapy strategies do not benefit most colorectal cancer patients and many triple‐negative breast cancer… read more here.

Keywords: three one; one nanoscale; chemo immunotherapy; cancer ... See more keywords

Robust Optimal Control-based Design of Combined Chemo- and Immunotherapy Delivery Profiles

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recommendations! Published in 2019 at "IFAC-PapersOnLine"

DOI: 10.1016/j.ifacol.2019.12.239

Abstract: Abstract This paper addresses the problem of drug injection schedules design for cancer treatment, in the presence of model parametric uncertainties. It is commonly known that achieving optimal recovery performances under uncertainties is a complex… read more here.

Keywords: chemo immunotherapy; control; robust optimal; control based ... See more keywords
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Front-line chemo-immunotherapy with carboplatin-paclitaxel using oregovomab indirect immunization in advanced ovarian cancer: A randomized phase II study.

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recommendations! Published in 2020 at "Gynecologic oncology"

DOI: 10.1016/j.ygyno.2019.12.024

Abstract: BACKGROUND This randomized phase II study tested the hypothesis that schedule dependent chemo-immunotherapy with oregovomab improves progression free survival (PFS) and overall survival (OS) in optimally resected, Stage III/IV ovarian cancer. METHODS Patients from both… read more here.

Keywords: chemo immunotherapy; study; randomized phase; ovarian cancer ... See more keywords

Co-Delivery of Doxorubicin and Anti-PD-L1 Peptide in Lipid/PLGA Nanocomplexes for the Chemo-Immunotherapy of Cancer.

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recommendations! Published in 2022 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.2c00611

Abstract: The combined delivery of chemotherapeutics with checkpoint inhibitors of the PD-1/PD-L1 pathway provides a new approach for cancer treatment. Small-molecule peptide inhibitors possess short production cycle, low immunogenicity, and fewer side effects; however, their potential… read more here.

Keywords: immunotherapy cancer; doxorubicin; plga; chemo immunotherapy ... See more keywords

Synergistic Chemo-Immunotherapy Using pH-Responsive Nanoparticles in Breast Cancer Treatment: In Vitro and In Vivo Studies.

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recommendations! Published in 2024 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.4c00723

Abstract: Recent research underscores the pivotal role of the heterogeneous multicellular interactome within the tumor microenvironment (TME) in tumor progression and survival. Tumor-associated macrophages (TAMs), among other nonmalignant cells in the TME, promote an immunosuppressive environment,… read more here.

Keywords: chemo immunotherapy; breast cancer; immunotherapy using; tumor ... See more keywords

Carrier-Free Nanoadjuvant-Loaded Bilayer Microneedles for Programmed and Individualized Cancer Chemo-Immunotherapy.

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recommendations! Published in 2025 at "Nano letters"

DOI: 10.1021/acs.nanolett.5c02670

Abstract: Triple-negative breast cancer (TNBC) exhibits low response rates to current immunotherapies. In this study, we present a double-layer dissolvable microneedle (MN) patch consisting of chemotherapeutic drugs in the shell layer and a carrier-free nanoadjuvant in… read more here.

Keywords: chemo immunotherapy; cancer; free nanoadjuvant; carrier ... See more keywords

Self-Assembled Immunostimulatory Tetrahedral Framework Nucleic Acid Vehicles for Tumor Chemo-immunotherapy.

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recommendations! Published in 2022 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.2c09462

Abstract: Some chemotherapeutic agents, such as anthracyclines and oxaliplatin, can induce immunogenic cell death (ICD) with additional immune responses against cancer. However, ICD-based immunotherapy is limited by the nonspecific distribution of drugs and various side effects.… read more here.

Keywords: immunotherapy; self assembled; tetrahedral framework; chemo immunotherapy ... See more keywords