Mitochondria and chronic effects of cancer therapeutics: The clinical implications
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02313-2
Abstract: One of the major mechanisms of action of chemo-radiation is to induce cellular senescence, which exerts crucial roles in age-related pathology. The concept of senescence is evolved, and the novel understanding of senescence-associated reprogramming/stemness has… read more here.
Keywords: chemo radiation; senescence; mitochondria chronic; cancer ... See more keywords
Deep neural networks for neuro-oncology: Towards patient individualized design of chemo-radiation therapy for Glioblastoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomedical informatics"
DOI: 10.1016/j.jbi.2022.104006
Abstract: BACKGROUND AND OBJECTIVES Glioblastoma multiforme (GBM) is the most common and deadly type of primary cancers of the brain and central nervous system in adults. Despite the importance of designing a personalized treatment regimen for… read more here.
Keywords: treatment regimen; deep neural; chemo radiation; treatment ... See more keywords
Swedish National Multicenter Study on Head and Neck Cancer of Unknown Primary: Prognostic Factors and Impact of Treatment on Survival
Sign Up to like & getrecommendations! Published in 2021 at "International Archives of Otorhinolaryngology"
DOI: 10.1055/s-0040-1712106
Abstract: Introduction Head and neck cancer of unknown primary (HNCUP) is a rare condition whose prognostic factors that are significant for survival vary between studies. No randomized treatment study has been performed thus far, and the… read more here.
Keywords: chemo radiation; prognostic factors; neck; treatment ... See more keywords
Postoperative adjuvant radiation for cervix cancer: reflections on the evidence and a peep into the future
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-002528
Abstract: Early stage cervical cancer, stages IB1–2 and IIA1, can be treated with (chemo)radiation and brachytherapy or radical hysterectomy with or without further adjuvant (chemo)radiation. In a carefully selected cohort for surgery, traditionally a small proportion… read more here.
Keywords: postoperative adjuvant; adjuvant radiation; chemo radiation; evidence ... See more keywords
ASO Author Reflections: The Sequential Radiographic Effects of Preoperative Chemotherapy and (Chemo)Radiation on Tumor Anatomy in Patients with Localized Pancreatic Cancer
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DOI: 10.1245/s10434-020-08531-5
Abstract: Radiographic downstaging of localized pancreatic adenocarcinoma has historically been an uncommon event following preoperative therapy. We previously identified only one patient among 122 who had a borderline resectable tumor that was downstaged to resectable after… read more here.
Keywords: chemotherapy; localized pancreatic; chemo radiation; anatomy ... See more keywords
Outcomes of Interventions for Angiosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.819099
Abstract: Objective Angiosarcoma is a rare malignant vascular tumor, and the management and outcome of this disease are not well-described. The aim of this study was to report the incidence, patient demographics, and outcomes of angiosarcoma… read more here.
Keywords: operation; interventions angiosarcoma; operation alone; outcomes interventions ... See more keywords
Bone Marrow-Sparing IMRT in Anal Cancer Patients Undergoing Concurrent Chemo-Radiation: Results of the First Phase of a Prospective Phase II Trial
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DOI: 10.3390/cancers12113306
Abstract: Simple Summary Hematological toxicity may be a consistent issue in anal cancer patients undergoing concurrent chemo-radiation, with a potentially detrimental effect on clinical outcomes and patient compliance to treatment. Chemotherapy is the most important trigger,… read more here.
Keywords: trial; chemo radiation; anal cancer; cancer patients ... See more keywords
Sarcopenia as a Prognostic Marker in Elderly Head and Neck Squamous Cell Carcinoma Patients Undergoing (Chemo-)Radiation
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DOI: 10.3390/cancers14225536
Abstract: Simple Summary Sarcopenia, i.e., the loss of muscle mass is a risk factor for reduced survival and increased treatment-associated toxicities in many cancers, and it increases with age. In this analysis, we investigated sarcopenia and… read more here.
Keywords: head neck; undergoing chemo; chemo radiation; sarcopenia ... See more keywords