Legitimizing a chemoattractant receptor
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.357.6356.1108-r
Abstract: Immunology The orphan receptor GPR15 mediates the trafficking of lymphocytes to the colon and skin and the recruitment of effector T cells to inflamed intestinal tissue. Using porcine colonic extracts, Suply et al. purified a… read more here.
Keywords: chemoattractant receptor; gpr15l; legitimizing chemoattractant; immunology ... See more keywords
Tyrosine sulfation and O-glycosylation of chemoattractant receptor GPR15 differentially regulate interaction with GPR15L.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.247833
Abstract: GPR15 is a G protein-coupled receptor (GPCR) that directs lymphocyte homing to the colon and skin. Recent studies have identified a chemokine-like protein C10orf99/GPR15L as a functional ligand of GPR15. In this study we examined… read more here.
Keywords: gpr15l; sulfation; interaction; receptor ... See more keywords
A G-protein-coupled chemoattractant receptor recognizes lipopolysaccharide for bacterial phagocytosis
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Biology"
DOI: 10.1371/journal.pbio.2005754
Abstract: Phagocytes locate microorganisms via chemotaxis and then consume them using phagocytosis. Dictyostelium amoebas are stereotypical phagocytes that prey on diverse bacteria using both processes. However, as typical phagocytic receptors, such as complement receptors or Fcγ… read more here.
Keywords: phagocytosis; coupled chemoattractant; protein coupled; receptor ... See more keywords