Reversal of Chemoresistance via Staged Liberation of Chemodrug and siRNA in Hierarchical Response to ROS Gradient
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DOI: 10.1002/adhm.202304130
Abstract: P‐glycoprotein (P‐gp)‐mediated multidrug resistance (MDR) often leads to the failure of antitumor chemotherapy, and codelivery of chemodrug with P‐gp siRNA (siP‐gp) represents a promising approach for treating chemoresistant tumors. To maximize the antitumor efficacy, it… read more here.
Keywords: chemodrug; staged liberation; chemodrug sirna; hierarchical response ... See more keywords