Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b00137
Abstract: FK506-binding proteins (FKBPs) are evolutionarily conserved proteins that display peptidyl-prolyl isomerase activities and act as coreceptors for immunosuppressants. Microbial macrophage-infectivity-potentiator (Mip)-type FKBPs can enhance infectivity. However, developing druglike ligands for FKBPs or Mips has proven… read more here.
Keywords: binding proteins; chemogenomic profiling; fk506 binding; profiling human ... See more keywords