Articles with "chemokines chemokine" as a keyword



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Chemokines and Chemokine Receptors in the Development of NAFLD.

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Published in 2018 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-10-8684-7_4

Abstract: Chemokines are chemo-attractants for leukocyte trafficking, growth, and activation in injured and inflammatory tissues. The chemokine system is comprised of 50 chemokine ligands and 20 cognate chemokine receptors. In the context of liver diseases, leukocytes,… read more here.

Keywords: development nafld; chemokine receptors; steatosis; chemokines chemokine ... See more keywords
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The role of chemokines and chemokine receptors in pulmonary arterial hypertension

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Published in 2019 at "British Journal of Pharmacology"

DOI: 10.1111/bph.14826

Abstract: Pulmonary arterial hypertension (PAH) is characterized by progressive pulmonary artery remodelling leading to increased right ventricular pressure overload, which results in right heart failure and premature death. Inflammation plays a central role in the development… read more here.

Keywords: arterial hypertension; pulmonary arterial; role; chemokine receptors ... See more keywords
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The significance of chemokines in diffuse large B-cell lymphoma: a systematic review and future insights.

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Published in 2019 at "Future oncology"

DOI: 10.2217/fon-2018-0514

Abstract: Despite the progress made in molecular and clinical research, patients with diffuse large B-cell lymphoma (DLBCL) still have a bad prognosis. Recently, chemokines/chemokine receptors have become the subject of interest in relation to DLBCL. Studies… read more here.

Keywords: large cell; chemokine receptors; diffuse large; chemokines chemokine ... See more keywords
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Targeting Chemokines and Chemokine Receptors in Melanoma and Other Cancers

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Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.02480

Abstract: The tumor microenvironment is highly heterogeneous. It is composed of a diverse array of immune cells that are recruited continuously into lesions. They are guided into the tumor through interactions between chemokines and their receptors.… read more here.

Keywords: chemokine receptors; immune cells; chemokines chemokine; targeting chemokines ... See more keywords
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Chemokines and chemokine receptors as promising targets in rheumatoid arthritis

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1100869

Abstract: Rheumatoid arthritis (RA) is an autoimmune disease that commonly causes inflammation and bone destruction in multiple joints. Inflammatory cytokines, such as IL-6 and TNF-α, play important roles in RA development and pathogenesis. Biological therapies targeting… read more here.

Keywords: promising targets; receptors promising; chemokines chemokine; rheumatoid arthritis ... See more keywords
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Chemokines and chemokine receptors in Behçet’s disease

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1109147

Abstract: Behçet’s disease (BD), a chronic vascular inflammatory disease, is characterized by the symptoms of ocular lesions, recurrent genital and oral ulcers, skin symptoms and arthritis in addition to neurological, intestinal and vascular involvement. The pathogenesis… read more here.

Keywords: beh disease; receptors beh; chemokines chemokine; disease ... See more keywords
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Chemokines as Regulators of Neutrophils: Focus on Tumors, Therapeutic Targeting, and Immunotherapy

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14030680

Abstract: Simple Summary Neutrophils are the main leukocyte subset present in human blood and play a fundamental role in the defense against infections. Neutrophils are also an important component of the tumor stroma because they are… read more here.

Keywords: regulators neutrophils; chemokines chemokine; chemokines regulators; chemokine receptors ... See more keywords
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Targeting Chemokines and Chemokine GPCRs to Enhance Strong Opioid Efficacy in Neuropathic Pain

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Published in 2022 at "Life"

DOI: 10.3390/life12030398

Abstract: Neuropathic pain (NP) originates from an injury or disease of the somatosensory nervous system. This heterogeneous origin and the possible association with other pathologies make the management of NP a real challenge. To date, there… read more here.

Keywords: chemokine; pain; opioid efficacy; neuropathic pain ... See more keywords