Curcumin and metforminâmediated chemoprevention of oral cancer is associated with inhibition of cancer stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22692
Abstract: Effective chemoprevention is critical for improving outcomes of oral cancer. As single agents, curcumin and metformin are reported to exhibit chemopreventive properties, in vitro as well as in patients with oral cancer. In this study,… read more here.
Keywords: cancer stem; curcumin metformin; oral cancer; treatment ... See more keywords
Identification of factors that influence the decision to take chemoprevention in patients with a significant family history of breast cancer: results from a patient questionnaire survey
Sign Up to like & getrecommendations! Published in 2021 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-020-06046-x
Abstract: Purpose Chemoprevention reduces the risk of developing breast cancer in women with increased family history (FH) risk of breast cancer. However, chemoprevention uptake remains low and the reasons for this remain unclear. Methods Patients with… read more here.
Keywords: decision; chemoprevention; questionnaire survey; breast cancer ... See more keywords
Development of a dietary formulation of the SHetA2 chemoprevention drug for mice
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0550-0
Abstract: SummaryDevelopment of cancer chemoprevention compounds requires enhanced consideration for toxicity and route of administration because the target population is healthy. The small molecule drug, SHetA2 (NSC 726189), exhibited in vivo chemoprevention activity and lack of… read more here.
Keywords: formulation sheta2; dietary formulation; chemoprevention; drug ... See more keywords
Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
Sign Up to like & getrecommendations! Published in 2021 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-021-00848-x
Abstract: To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the… read more here.
Keywords: tobacco related; chemoprevention; chemoprevention precision; immunoprevention ... See more keywords
Specialist recommendation for chemoprevention medications in patients at familial risk of breast cancer: a cross-sectional survey in England
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Community Genetics"
DOI: 10.1007/s12687-020-00490-4
Abstract: In England, the National Institute for Health and Care Excellence guideline for familial breast cancer recommends chemoprevention for women at high and moderate familial risk of breast cancer. However, prescribing of chemoprevention has not improved… read more here.
Keywords: risk; primary care; chemoprevention; survey ... See more keywords
The use of natural compounds for the targeting and chemoprevention of ovarian cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.09.050
Abstract: Among gynaecological cancers, ovarian cancer represents the leading cause of death in women. Current treatment for ovarian cancer entails surgery followed by combined chemotherapy with platinum and taxane, which are associated, particularly cisplatin, with severe… read more here.
Keywords: natural compounds; treatment; chemoprevention; use natural ... See more keywords
Cancer chemoprevention revisited: Cytochrome P450 family 1B1 as a target in the tumor and the microenvironment.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer treatment reviews"
DOI: 10.1016/j.ctrv.2017.10.013
Abstract: Cancer chemoprevention is the use of synthetic, natural or biological agents to prevent or delay the development or progression of malignancies. Intriguingly, many phytochemicals with anti-inflammatory and anti-angiogenic effects, recently proposed as chemoprevention strategies, are… read more here.
Keywords: cancer chemoprevention; chemoprevention; family; cancer ... See more keywords
Phytochemical compounds targeting on Nrf2 for chemoprevention in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173588
Abstract: Colorectal cancer (CRC) has become one of the major factors of tumor-related morbidity and mortality in the world because of its poor prognosis and consequences of metastatic spread. Currently, chemoprevention has been considered as a… read more here.
Keywords: colorectal cancer; chemoprevention; targeting nrf2; cancer ... See more keywords
Topical agents for oral cancer chemoprevention: A systematic review of the literature.
Sign Up to like & getrecommendations! Published in 2017 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2017.02.014
Abstract: OBJECTIVES/HYPOTHESIS We review the use of topical chemoprevention agents in patients with oral potentially malignant disorders (PMD). METHODS A systematic review of studies on topical chemoprevention agents for oral PMD from 1946 to November 2016… read more here.
Keywords: agents oral; systematic review; chemoprevention; review ... See more keywords
Hepatocellular Carcinoma Chemoprevention with Generic Agents
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in Liver Disease"
DOI: 10.1055/a-1942-6693
Abstract: Liver cancer, mainly hepatocellular carcinoma (HCC), remains a major cause of cancer-related death worldwide. With the global epidemic of obesity, the major HCC etiologies have been dynamically shifting from viral to metabolic liver diseases. This… read more here.
Keywords: hepatocellular carcinoma; generic agents; hcc; chemoprevention ... See more keywords
M10, a novel derivative of Myricetin, prevents ulcerative colitis and colorectal tumor through attenuating robust endoplasmic reticulum stress
Sign Up to like & getrecommendations! Published in 2018 at "Carcinogenesis"
DOI: 10.1093/carcin/bgy057
Abstract: Chronic gut inflammation disposes to an increased risk of colitis-associated cancer. Chemoprevention is an attractive complementary strategy. We aimed to evaluate the chemopreventive effects of M10, a novel derivative of Myricetin, in the murine azoxymethane/dextran… read more here.
Keywords: colorectal tumor; chemoprevention; colitis colorectal; m10 ... See more keywords