Epigenetic‐mediated immune suppression of positive co‐stimulatory molecules in chemoresistant ovarian cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10729
Abstract: The immunological response against cancer is a critical balance between immune‐activating and immune‐suppressing mechanisms. Ovarian cancer creates a suppressive microenvironment to escape immune elimination; however, the molecular mechanisms are poorly understood, and it is unclear… read more here.
Keywords: chemoresistant ovarian; 40l 1bbl; ovarian cancer; expression ... See more keywords
Heat Shock Protein 60 (HSP60) Serves as a Potential Target for the Sensitization of Chemoresistant Ovarian Cancer Cells
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-019-00089-2
Abstract: HSP60 is a mitochondrial chaperone protein that is associated with decreased overall survival of ovarian cancer patients. We determined whether targeting HSP60 with its monoclonal antibody would induce cytotoxicity in sensitive and chemoresistant ovarian cancer… read more here.
Keywords: antibody; target; chemoresistant ovarian; ovarian cancer ... See more keywords
Epigenetic regulation of RGS2 (Regulator of G-protein signaling 2) in chemoresistant ovarian cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Chemotherapy"
DOI: 10.1080/1120009x.2016.1277007
Abstract: Regulator of G-protein signaling 2 (RGS2) is a GTPase-activating protein functioning as an inhibitor of G-protein coupled receptors (GPCRs). RGS2 dysregulation was implicated in solid tumour development and RGS2 downregulation has been reported in prostate… read more here.
Keywords: protein; chemoresistant ovarian; rgs2; ovarian cancer ... See more keywords