Labeling Proteins at Site-Specifically Incorporated 5-Hydroxytryptophan Residues Using a Chemoselective Rapid Azo-Coupling Reaction.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9654-4_16
Abstract: Chemoselective protein labeling is a valuable tool in the arsenal of modern chemical biology. The unnatural amino acid mutagenesis technology provides a powerful way to site-specifically introduce nonnatural chemical functionalities into recombinant proteins, which can… read more here.
Keywords: rapid azo; chemoselective rapid; site specifically; biology ... See more keywords
A Chemoselective Rapid Azo-Coupling Reaction (CRACR) for Unclickable Bioconjugation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b05125
Abstract: Chemoselective modification of complex biomolecules has become a cornerstone of chemical biology. Despite the exciting developments of the past two decades, the demand for new chemoselective reactions with unique abilities, and those compatible with existing… read more here.
Keywords: bioconjugation; azo coupling; chemoselective rapid; coupling reaction ... See more keywords