Synthesis of non-symmetrical alkynylpyridines by chemoselective Sonogashira cross-coupling reactions
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DOI: 10.1016/j.tet.2019.130559
Abstract: Abstract 4-Bromo-2,3,5-trichloro-6-iodopyridine was studied as a new substrate in chemoselective Sonogashira reactions. This approach provides an efficient access to non-symmetrical mono-, di-, tri- and pentaalkynylated pyridines in good yields. Selected pentaalkynylated pyridines were studied with… read more here.
Keywords: synthesis non; non symmetrical; symmetrical alkynylpyridines; alkynylpyridines chemoselective ... See more keywords