Chemoselective synthesis, X-ray characterization and DFT studies of new organic single crystal: S-(2-aminophenyl) cyclohexylcarbamothioate
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.127499
Abstract: Abstract Chemoselective manner of 2-aminothiophenol reaction with cyclohexyl isocyanate under the different conditions was investigated. The product, S-(2-aminophenyl) cyclohexylcarbamothioate, was characterized by 1H, 13C NMR, FT-IR, HRMS and single crystal X-ray diffraction analysis. Single crystal… read more here.
Keywords: ray; aminophenyl cyclohexylcarbamothioate; single crystal; chemoselective synthesis ... See more keywords
Chemoselective Synthesis of Sulfenylated Spiroindolenines from Indolyl-ynones via Organosulfenyl Chloride-Mediated Dearomatizing Spirocyclization.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04063
Abstract: A metal-free sulfenylation/spirocyclization of indolyl-ynones realized by organosulfenyl chloride, generated in situ from the reaction of disulfides and PhICl2, is presented. This cascade one-pot process enables a chemoselective synthesis of diverse sulfenylated spiroindolenines depending on… read more here.
Keywords: indolyl ynones; chemoselective synthesis; spirocyclization; sulfenylated spiroindolenines ... See more keywords
A trisulfur radical anion (S3˙-) involved sulfur insertion reaction of 1,3-enynes: sulfide sources control chemoselective synthesis of 2,3,5-trisubstituted thiophenes and 3-thienyl disulfides.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc03604k
Abstract: Cascade cyclization reactions of S3˙- in situ generated from S2- with 1,3-enynes for the chemoselective synthesis of 2,3,5-trisubstituted thiophenes and 3-thienyl disulfides controlled by sulfide salts are developed. These two protocols provide new, environment-friendly and… read more here.
Keywords: thiophenes thienyl; thienyl disulfides; synthesis trisubstituted; trisubstituted thiophenes ... See more keywords
SuFEx-enabled, chemoselective synthesis of triflates, triflamides and triflimidates
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d1sc06267k
Abstract: Sulfur(vi) Fluoride Exchange (SuFEx) chemistry has emerged as a next-generation click reaction, designed to assemble functional molecules quickly and modularly. Here, we report the ex situ generation of trifluoromethanesulfonyl fluoride (CF3SO2F) gas in a two… read more here.
Keywords: 320 320; sufex enabled; chemoselective synthesis; triflates triflamides ... See more keywords
Chemoselective Synthesis of N-(Aminoalkyl/amidino)phenyl Naphthalene-1-carboxamides and 5,6,7,8-Tetrahydronaphthalene-1-carboxamides and Their Anticoagulant Screening
Sign Up to like & getrecommendations! Published in 2017 at "Synlett"
DOI: 10.1055/s-0036-1588517
Abstract: N-[(Aminoalkyl)phenyl]-1-naphthamides and N-[(aminoalkyl)phenyl]-5,6,7,8-tetrahydronaphthalene-1-carboxamides were selectively synthesized from the corresponding cyanonaphthamides by catalytic hydrogenation. N-(Amidinophenyl)-1-naphthalenecarboxamides and N-(amidinophenyl)-5,6,7,8-tetrahydronaphthalene-1-carboxamides were chemoselectively obtained from the corresponding O-acetylamidoximes or amidoximes, respectively, by catalytic hydrogenation. The products were screened for their… read more here.
Keywords: tetrahydronaphthalene carboxamides; synthesis aminoalkyl; phenyl; aminoalkyl amidino ... See more keywords