Heterogeneous Enantioselective Hydrogenation of Aromatic Ketones Catalyzed by Rh Nanoparticles Immobilized in Ionic Liquid
Sign Up to like & getrecommendations! Published in 2019 at "Catalysis Letters"
DOI: 10.1007/s10562-019-02768-w
Abstract: Rhodium nanoparticles (Rh NPs) stabilized by natural cinchona alkaloids were synthesized in imidazolium-based ionic liquids using H2 as the reductant. Characterization showed well-dispersed Rh NPs of about 1.96 nm (TEM and HRTEM) and confirmed the ionic… read more here.
Keywords: enantioselectivity; ionic liquid; chemoselectivity; hydrogenation ... See more keywords
Chelate ring size effects of Ir(P,N,N) complexes: Chemoselectivity switch in the asymmetric hydrogenation of α,β-unsaturated ketones
Sign Up to like & getrecommendations! Published in 2020 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2020.106128
Abstract: Abstract A novel, highly modular approach has been developed for the synthesis of new chiral P,N,N ligands with the general formula Ph2P(CH3)CH(CH2)mCH(CH3)NHCH2CH2(CH2)nN(CH3)2 and Ph2P(CH3)CHCH2CH(CH3)NHCH2(CH2)n-2-Py (m, n = 0, 1). The systematic variation of their P N and… read more here.
Keywords: chemoselectivity; ch3; unsaturated ketones; switch ... See more keywords
Chemoselective oxidation of unsaturated organosulfur, selenium and phosphorus compounds by molybdenum oxodiperoxo complexes: A computational investigation
Sign Up to like & getrecommendations! Published in 2017 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2017.08.021
Abstract: Abstract Oxidation is fundamental for many chemical processes and the search for chemoselective oxidants is relevant because most substrates have different functional groups. For unsaturated organo-heteroatom (E) substrates R 1 E(CH 2 ) n CH… read more here.
Keywords: unsaturated organosulfur; oxidation; chemoselectivity; chemoselective oxidation ... See more keywords
Origins of chemoselectivity of Rh(III)-Catalyzed C–H activation of N-(pivaloyloxy)benzamide: Insights from density functional theory calculations
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2018.11.011
Abstract: Abstract An unprecedented Rh(III)-catalyzed C–H activation of N-(pivaloyloxy)benzamide was recently reported by Feng et al. In this transformation, the substituent on the alkyne controls the chemoselectivity (annulation or hydroarylation). Given the importance of this novel strategy,… read more here.
Keywords: iii catalyzed; chemoselectivity; catalyzed activation; activation pivaloyloxy ... See more keywords
Tuning acylthiourea ligands in Ru(II) catalysts for altering the reactivity and chemoselectivity of transfer hydrogenation reactions, and synthesis of 3-isopropoxy-1H-indole through a new synthetic approach
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2019.121087
Abstract: Abstract Ru(II)-p-cymene complexes (1–3) containing picolyl based pseudo-acylthiourea ligands (L1-L3) were synthesized and characterized. The crystallographic study confirmed the molecular structures of all the ligands (L1-L3) and complex 3. The catalytic activity of the complexes… read more here.
Keywords: chemoselectivity; ligands catalysts; reactivity; tuning acylthiourea ... See more keywords
Three-Way Chemoselectivity Switching through Coupled Equilibria.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02003
Abstract: Controlling the chemoselectivity of reactions operating on complex mixtures, including those found in biological and petrochemical feedstocks or in the primordial soup from which life emerged, is generally challenging. The selectivity of imine oxidation can… read more here.
Keywords: three way; chemoselectivity; coupled equilibria; chemoselectivity switching ... See more keywords
Engineering Chemoselectivity in Hemoprotein-Catalyzed Indole Amidation.
Sign Up to like & getrecommendations! Published in 2019 at "ACS catalysis"
DOI: 10.1021/acscatal.9b02508
Abstract: Here we report a cytochrome P450 variant that catalyzes C2-amidation of 1-methylindoles with tosyl azide via nitrene transfer. Before evolutionary optimization the enzyme exhibited two undesired side reactivities resulting in reduction of the putative iron-nitrenoid… read more here.
Keywords: chemoselectivity; chemoselectivity hemoprotein; indole amidation; engineering chemoselectivity ... See more keywords
Differences in chemoselectivity in olefin oxidation by a series of non-porphyrin manganese(IV)-oxo complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt00876a
Abstract: High valent metal-oxo intermediates are versatile oxidants known to facilitate both oxygen atom transfer (OAT) and hydrogen atom transfer (HAT) reactions in nature. In addition to performing essential yet challenging biological reactions, these intermediates are… read more here.
Keywords: oxidation; mniv oxo; chemoselectivity; oxo ... See more keywords
Heme compound II models in chemoselectivity and disproportionation reactions
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc01232d
Abstract: Heme compound II models bearing electron-deficient and -rich porphyrins, [FeIV(O)(TPFPP)(Cl)]− (1a) and [FeIV(O)(TMP)(Cl)]− (2a), respectively, are synthesized, spectroscopically characterized, and investigated in chemoselectivity and disproportionation reactions using cyclohexene as a mechanistic probe. Interestingly, cyclohexene oxidation… read more here.
Keywords: 320 320; compound; disproportionation; chemoselectivity ... See more keywords
Switching the chemoselectivity of perakine reductase for selective reduction of α,β-unsaturated ketones by Arg127 mutation.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00850a
Abstract: The chemoselectivity of perakine reductase (PR) was engineered through rational design. We identified Arg127 as a control site of chemoselectivity. Mutation of Arg127 switched the chemoselectivity of PR between CO and CC or led to… read more here.
Keywords: perakine reductase; unsaturated ketones; chemoselectivity; chemoselectivity perakine ... See more keywords