DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53-deficient pancreatic cancer cells
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DOI: 10.3892/mmr.2017.7923
Abstract: The aberrant expression of DNA methyltransferases (DNMTs) has been considered to be associated with pancreatic carcinogenesis and progression. DNMT3a is widely involved in cell proliferation and cell cycle progression in pancreatic ductal adenocarcinoma (PDAC) cells.… read more here.
Keywords: gem; chemosensitivity; chemosensitivity gemcitabine; p53 deficient ... See more keywords