The effects of chemotherapeutic drugs on PD-L1 gene expression in breast cancer cell lines
Sign Up to like & getrecommendations! Published in 2021 at "Medical Oncology"
DOI: 10.1007/s12032-021-01556-0
Abstract: Breast cancer is the most common cancer among women in terms of prevalence and mortality, and chemotherapy is one of the most effective treatments at higher stages. However, resistance to chemotherapy is the main obstacle… read more here.
Keywords: chemotherapy drugs; breast cancer; expression; cancer ... See more keywords
3D Printed Absorber for Capturing Chemotherapy Drugs before They Spread through the Body
Sign Up to like & getrecommendations! Published in 2019 at "ACS Central Science"
DOI: 10.1021/acscentsci.8b00700
Abstract: Despite efforts to develop increasingly targeted and personalized cancer therapeutics, dosing of drugs in cancer chemotherapy is limited by systemic toxic side effects. We have designed, built, and deployed porous absorbers for capturing chemotherapy drugs… read more here.
Keywords: chemotherapy; capturing chemotherapy; chemotherapy drugs; body ... See more keywords
Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK directed activation of NF-κB
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-01583-7
Abstract: The mutagenic APOBEC3B (A3B) cytosine deaminase is frequently over-expressed in cancer and promotes tumour heterogeneity and therapy resistance. Hence, understanding the mechanisms that underlie A3B over-expression is important, especially for developing therapeutic approaches to reducing… read more here.
Keywords: chemotherapy drugs; dna; a3b expression; expression ... See more keywords
Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Human Reproduction"
DOI: 10.1093/molehr/gaaa008
Abstract: Abstract The treatment of childhood cancer with chemotherapy drugs can result in infertility in adulthood. Newer generations of drugs are developed to replace parent drugs, with the potential benefits of less toxic side effects. For… read more here.
Keywords: chemotherapy drugs; cisplatin; cisplatin carboplatin; carboplatin ... See more keywords
Development and psychometric testing of the safety climate instrument suitable for nurses handling chemotherapy drugs.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of advanced nursing"
DOI: 10.1111/jan.15257
Abstract: AIM To develop and test the psychometric properties of the Taiwanese safety climate instrument suitable for nurses handling chemotherapy drugs. DESIGN This is an instrument development study. METHOD All four stages, including questionnaire design, expert… read more here.
Keywords: chemotherapy drugs; handling chemotherapy; safety climate; instrument ... See more keywords
The safe handling of chemotherapy drugs in low- and middle-income countries: An overview of practices
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155221995539
Abstract: Introduction The rising burden of cancer in low- and middle-income countries (LMICs) has led to substantial efforts to improve access to chemotherapy. The present study’s objectives were to obtain an overview of the safe handling… read more here.
Keywords: safe handling; chemotherapy; income; middle income ... See more keywords
A review of medical devices used for safe chemotherapy applications: Focus on ONCOERA® IV GROUP products
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/10781552221147694
Abstract: Objective The healthcare workers and the workers in the manufacturing industry of chemotherapy drugs are exposed to the “hazardous” effects of these drugs during production, transportation, distribution, administration, and disposal. In order to be protected… read more here.
Keywords: chemotherapy drugs; medical devices; used safe; review medical ... See more keywords
Silencing the PIK3CA Gene Enhances the Sensitivity of Childhood Leukemia Cells to Chemotherapy Drugs by Suppressing the Phosphorylation of Akt
Sign Up to like & getrecommendations! Published in 2019 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2019.60.2.182
Abstract: Purpose This study aimed to investigate the effects of PIK3CA on the sensitivity of acute B lymphocytic leukemia cells (Nalm-6 cells) to chemotherapy drugs. Materials and Methods Children's normal B lymphocytes and Nalm-6 cells were… read more here.
Keywords: chemotherapy drugs; leukemia cells; group; sensitivity ... See more keywords
The Measurement and Analysis of Impedance Response of HeLa Cells to Distinct Chemotherapy Drugs
Sign Up to like & getrecommendations! Published in 2021 at "Micromachines"
DOI: 10.3390/mi12020202
Abstract: Electric cell–substrate impedance sensing exhibits a real-time and label-free feature to monitor the response of cells stimulated by various biochemical and mechanical signals. Alterations in the currents passing through the cell–electrode system characterize the impedance… read more here.
Keywords: response; chemotherapy drugs; impedance; cell ... See more keywords