Treatment of Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia-From Intensive Chemotherapy Combinations to Chemotherapy-Free Regimens: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.2398
Abstract: Importance With the advent of potent BCR::ABL1 tyrosine kinase inhibitors (TKIs), Philadelphia chromosome-positive (Ph-positive) acute lymphoblastic leukemia (ALL) is now a relatively favorable-risk acute leukemia. In this review, we discuss the current evidence for frontline… read more here.
Keywords: acute; allogeneic sct; free regimens; chemotherapy free ... See more keywords
Rituximab: a benchmark in the development of chemotherapy-free treatment strategies for follicular lymphomas
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DOI: 10.1093/annonc/mdx768
Abstract: Background With the introduction of the anti-CD20 antibody rituximab, the outcome of patients with follicular lymphoma (FL) has greatly improved over the last two decades. First-line prolonged rituximab monotherapy is effective, achieving long-term remission and… read more here.
Keywords: chemotherapy; rituximab; treatment; chemotherapy free ... See more keywords
Novel chemotherapy‐free combination regimen for ibrutinib‐resistant mantle cell lymphoma
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DOI: 10.1111/bjh.14669
Abstract: Ian Jennings David Perry Henry Watson Raza Alikhan Mike Laffan Keith Gomez Steve Kitchen Isobel Walker and on behalf of the Haemostasis and Thrombosis Task Force of the British Society for Haematology & UK NEQAS… read more here.
Keywords: free combination; haematology; hospital; combination regimen ... See more keywords
Chemotherapy-free treatment of recurrent advanced ovarian cancer: myth or reality?
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DOI: 10.1136/ijgc-2022-003719
Abstract: Advanced ovarian cancer remains a leading cause of death from gynecologic malignancy. Surgery and, in most cases, platinum-based chemotherapy with or without maintenance with bevacizumab and/or poly-ADP ribose polymerase inhibitors (PARPi) represent the mainstay of… read more here.
Keywords: ovarian cancer; advanced ovarian; chemotherapy free; treatment ... See more keywords
The potential for chemotherapy-free strategies in mantle cell lymphoma.
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DOI: 10.1182/blood-2017-05-737510
Abstract: Mantle cell lymphoma (MCL) may be 1 of the few cancers for which multiple chemotherapy and nonchemotherapy regimens are considered as standard. Despite the significant activity of chemotherapy in the first-line setting and beyond, its… read more here.
Keywords: chemotherapy; potential chemotherapy; chemotherapy free; mantle cell ... See more keywords
Chemotherapy-free treatment for acute promyelocytic leukemia: the pediatric view of a revolutionary tale
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DOI: 10.3389/fonc.2023.1135350
Abstract: The addition of all-trans retinoic acid (ATRA) to the standard anthracycline-base chemotherapy has revolutionized the treatment of acute promyelocytic leukemia (APL) over the last decades, becoming a model for precision medicine. The protocols based on… read more here.
Keywords: medicine; promyelocytic leukemia; chemotherapy free; acute promyelocytic ... See more keywords
Chemotherapy-Free Targeted Anti-BCR-ABL+ Acute Lymphoblastic Leukemia Therapy May Benefit the Heart
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DOI: 10.3390/cancers14040983
Abstract: Simple Summary Risk-adapted multiagent chemotherapy has led to a remarkable improvement in the life expectancy of patients with acute lymphoblastic leukemia (ALL). Nevertheless, in high-risk subgroups such as BCR-ABL+ ALL, relapse rates remain high without… read more here.
Keywords: chemotherapy free; lymphoblastic leukemia; acute lymphoblastic; bcr abl ... See more keywords
A chemotherapy-free regimen improves prognosis in elderly diffuse large B-cell lymphoma patients with a low-performance status score: A Chinese multi-center real-world study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_2388_21
Abstract: Background: Because patients with diffuse large B-cell lymphoma (DLBCL) aged >80 years old typically experience dismal outcomes, it is essential to improve disease control and reduce side effects in such patients. Methods: This was a… read more here.
Keywords: center; group; large cell; diffuse large ... See more keywords