Impact of chemotherapy and/or immunotherapy on neutralizing antibody response to SARS‐CoV‐2 mRNA‐1237 vaccine in patients with solid tumors
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13359
Abstract: Patients with solid tumors have been a risk group since the beginning of the SARS‐CoV‐2 pandemic due to more significant complications, hospitalizations or deaths. The immunosuppressive state of cancer treatments or the tumor itself could… read more here.
Keywords: patients solid; mrna 1237; chemotherapy immunotherapy; solid tumors ... See more keywords
Encapsulation of Platinum Prodrugs into PC7A Polymeric Nanoparticles Combined with Immune Checkpoint Inhibitors for Therapeutically Enhanced Multimodal Chemotherapy and Immunotherapy by Activation of the STING Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202205241
Abstract: Tumor immunotherapy has emerged as one of the most promising therapeutic methods to treat cancer. Despite its clinical application, the immunosuppressive tumor microenvironment compromises the therapeutic efficiency of this technique. To overcome this limitation, many… read more here.
Keywords: immune checkpoint; immunotherapy; therapeutically enhanced; sting pathway ... See more keywords
Do we still need CRS and HIPEC in colorectal cancer in times of modern chemotherapy and immunotherapy?
Sign Up to like & getrecommendations! Published in 2020 at "memo - Magazine of European Medical Oncology"
DOI: 10.1007/s12254-020-00647-4
Abstract: Peritoneal carcinomatosis from colorectal cancer is associated with a poor prognosis and is usually treated with systemic chemotherapy and immunotherapy alone. In patients with isolated peritoneal carcinomatosis (PC) without nonperitoneal metastases, however, cytoreductive surgery (CRS)… read more here.
Keywords: chemotherapy; colorectal cancer; chemotherapy immunotherapy; cancer ... See more keywords
Consolidative Thoracic Radiation Therapy After First-Line Chemotherapy and Immunotherapy in Extensive-Stage Small Cell Lung Cancer: A Multi-Institutional Case Series
Sign Up to like & getrecommendations! Published in 2022 at "Advances in Radiation Oncology"
DOI: 10.1016/j.adro.2021.100883
Abstract: Purpose Survival for patients with extensive-stage small cell lung cancer (ES-SCLC) remains poor. Consolidative thoracic radiation therapy (cTRT) and upfront immunotherapy with chemotherapy have each incrementally improved patient outcomes, but have not yet been combined… read more here.
Keywords: chemotherapy immunotherapy; immunotherapy; line chemotherapy; first line ... See more keywords
Developing a Novel Anticancer Gold(III) Agent to Integrate Chemotherapy and Immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00050
Abstract: To effectively treat gastric cancer, we innovatively attempted to develop a metal agent to integrate immunotherapy and chemotherapy by dual targeting the cellular components in the tumor microenvironment (TME) based on the specific residue of… read more here.
Keywords: agent; immunotherapy; integrate chemotherapy; chemotherapy immunotherapy ... See more keywords
Tumor Microenvironment Responsive Nanogel for the Combinatorial Antitumor Effect of Chemotherapy and Immunotherapy.
Sign Up to like & getrecommendations! Published in 2017 at "Nano letters"
DOI: 10.1021/acs.nanolett.7b03186
Abstract: A biomimetic nanogel with tumor microenvironment responsive property is developed for the combinatorial antitumor effects of chemotherapy and immunotherapy. Nanogels are formulated with hydroxypropyl-β-cyclodextrin acrylate and two opposite charged chitosan derivatives for entrapping anticancer drug… read more here.
Keywords: microenvironment responsive; chemotherapy immunotherapy; tumor microenvironment; combinatorial antitumor ... See more keywords
The utility of chemotherapy after immunotherapy failure in metastatic melanoma: A multicenter case series.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e21588
Abstract: e21588Background: Immune checkpoint inhibitors are standard of care for most patients (pts) with MM, yet only a minority has durable disease control. CTX has limited activity when used first-line, ... read more here.
Keywords: melanoma multicenter; utility chemotherapy; immunotherapy failure; metastatic melanoma ... See more keywords
DNA damage repair gene mutations predict the efficacy of platinum-based chemotherapy and immunotherapy plus platinum-based chemotherapy in advanced non-small cell lung cancer: a retrospective Chinese cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Translational Lung Cancer Research"
DOI: 10.21037/tlcr-22-746
Abstract: Background Platinum-based chemotherapy (PC) and immunotherapy plus platinum-based chemotherapy (IPC) remain the first-line treatment for advanced NSCLC. But only a minority patients benefit from PC, and existing biomarkers, such as PD-L1, have been shown to… read more here.
Keywords: ddr; chemotherapy immunotherapy; platinum based; based chemotherapy ... See more keywords
SCG2: A Prognostic Marker That Pinpoints Chemotherapy and Immunotherapy in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.873871
Abstract: Background Fluorouracil (FU)-based chemotherapy regimens are indispensable in the comprehensive treatment of colorectal cancer (CRC). However, the heterogeneity of treated individuals and the severe adverse effects of chemotherapy results in limited overall benefit. Methods Firstly,… read more here.
Keywords: expression; scg2; colorectal cancer; chemotherapy immunotherapy ... See more keywords
Effects of chemotherapy and immunotherapy on microbial diversity in TME and engineered bacterial-mediated tumor therapy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1084926
Abstract: Tumor microbiota is a group of microorganisms located in tumor tissues with rich diversity that can promote tumorigenesis and development, and different types of tumors have different tumor microbiotas, which has important implications for tumor… read more here.
Keywords: tumor microbiota; diversity; effects chemotherapy; chemotherapy immunotherapy ... See more keywords
Chemobrain, Olfactory and Lifestyle Assessment in Onco-Geriatrics: Sex-Mediated Differences between Chemotherapy and Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12101390
Abstract: A possible link between chemotherapy and cognitive impairment has been identified. In the literature, this condition is usually called chemobrain and can mostly affect some memory domain but can lead also to other cognitive impairments.… read more here.
Keywords: olfactory lifestyle; immunotherapy; onco; chemobrain olfactory ... See more keywords