Articles with "chemotherapy parp" as a keyword



ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib

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Published in 2022 at "Cancer Research"

DOI: 10.1158/0008-5472.can-21-2997

Abstract: This detailed preclinical investigation, including pharmacokinetics/pharmacodynamics and dose–schedule optimizations, of AZD6738/ceralasertib alone and in combination with chemotherapy or PARP inhibitors can inform ongoing clinical efforts to treat cancer with ATR inhibitors. read more here.

Keywords: azd6738 ceralasertib; chemotherapy parp; combination chemotherapy; inhibitor ... See more keywords