Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells
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DOI: 10.1194/jlr.ra119000251
Abstract: The combination of daunorubicin (dnr) and cytarabine (Ara-C) is a cornerstone of treatment for acute myelogenous leukemia (AML); resistance to these drugs is a major cause of treatment failure. Ceramide, a sphingolipid (SL), plays a… read more here.
Keywords: chemotherapy selection; dnr; resistant cells; selection pressure ... See more keywords