Synthesis of functionalized spirocyclic oxetanes through Paternò-Büchi reactions of cyclic ketones and maleic acid derivatives.
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DOI: 10.1039/d2cc06459f
Abstract: A telescoped three-step sequence to functionalised spirocyclic oxetanes is reported, involving Paternò-Büchi reactions between maleic acid derivatives and cyclic ketones. p-Xylene suppresses the competing alkene dimerization that has plagued previous work, allowing access to 35… read more here.
Keywords: patern chi; spirocyclic oxetanes; chi reactions; cyclic ketones ... See more keywords