Continual circulation of ECSA genotype and identification of a novel mutation I317V in the E1 gene of Chikungunya viral strains in southern India during 2015‐2016
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25662
Abstract: Chikungunya, a mosquito‐borne disease caused by Chikungunya virus (CHIKV), continues to be a significant public health problem in India. In 2016, 56 000 cases were reported from India, the largest number since the reemergence of CHIKV… read more here.
Keywords: chikv; india; 2015 2016; india 2015 ... See more keywords
Evaluation of analgesic and prophylactic activity of curcumin against chikungunya‐infected acute/chronic arthralgic mice
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28661
Abstract: Chikungunya virus (CHIKV) infection, a global public health problem, might lead to acute/chronic polyarthritis causing long‐term morbidity among infected patients. But, except nonsteroidal anti‐inflammatory drugs (NSAIDs) with gastrointestinal, cardiovascular, and immune‐related side‐effects, no Food and… read more here.
Keywords: curcumin; chikv induced; acute chronic; mice ... See more keywords
Genome sequences of chikungunya virus isolates circulating in midwestern Brazil
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Virology"
DOI: 10.1007/s00705-019-04174-4
Abstract: Chikungunya virus (CHIKV) is a reemerging arbovirus of the family Togaviridae that causes CHIKV fever, a disease that can extend from weeks to years depending on whether clinical signs of arthralgia persist. CHIKV is mainly… read more here.
Keywords: chikv; circulating midwestern; chikungunya virus; isolates circulating ... See more keywords
Neurologic Manifestation of Chikungunya Virus
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DOI: 10.1007/s11908-017-0561-1
Abstract: Purpose of ReviewChikungunya virus (CHIKV) is a RNA arbovirus that typically causes fevers and arthralgias, but reports of neurologic findings have become increasingly common. This article reviews our current understanding of CHIKV-associated neurologic manifestations.Recent FindingsIn… read more here.
Keywords: manifestation chikungunya; neurologic manifestation; chikv; disease ... See more keywords
Anti-viral Activities of Oroxylum indicum Extracts on Chikungunya Virus Infection
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DOI: 10.1007/s12088-017-0695-8
Abstract: Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus that poses a threat to human worldwide. Driven by the lack of approved medication and vaccination, research on anti-Chikungunya agents has received great attention. In an effort… read more here.
Keywords: anti viral; chikv; oroxylum indicum; indicum extracts ... See more keywords
NMR study of non-structural proteins–part III: 1H, 13C, 15N backbone and side-chain resonance assignment of macro domain from Chikungunya virus (CHIKV)
Sign Up to like & getrecommendations! Published in 2018 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-017-9775-2
Abstract: Macro domains are conserved protein domains found in eukaryotic organisms, bacteria, and archaea as well as in certain viruses. They consist of 130–190 amino acids and can bind ADP-ribose. Although the exact role of these… read more here.
Keywords: chikv; non structural; macro domain; macro ... See more keywords
Chikungunya virus infection induces differential inflammatory and antiviral responses in human monocytes and monocyte-derived macrophages.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105619
Abstract: Chikungunya virus (CHIKV) is a zoonotic arthropod-borne virus that has caused several outbreaks in tropical and subtropical areas worldwide during the last 50 years. The virus is known to target different human cell types throughout… read more here.
Keywords: chikv; infection; monocyte derived; chikungunya virus ... See more keywords
Intraviral interactome of Chikungunya virus reveals the homo-oligomerization and palmitoylation of structural protein TF
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and Biophysical Research Communications"
DOI: 10.1016/j.bbrc.2019.04.098
Abstract: Abstract Chikungunya virus (CHIKV) is a re-emerging mosquito-transmitted RNA virus causing joint and muscle pain. Although the protein-protein interactions (PPIs) between nonstructural proteins of CHIKV have been extensively established, the complete CHIKV intraviral interactome remains… read more here.
Keywords: palmitoylation; homo oligomerization; chikv; intraviral interactome ... See more keywords
In-silico prediction of novel drug-target complex of nsp3 of CHIKV through molecular dynamic simulation
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DOI: 10.1016/j.heliyon.2020.e04720
Abstract: Literature reported that nsp3 of CHIKV is an important target for the designing of drug as it involves in the replication, survival etc. Herein, about eighteen million molecules available in the ZINC database are filtered… read more here.
Keywords: chikv; target; nsp3 chikv; drug ... See more keywords
Detection of SARS-CoV-2 IgM Antibodies in Febrile Patients From an Endemic Region of Dengue and Chikungunya
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DOI: 10.1016/j.ijid.2021.12.128
Abstract: Purpose The rapid expansion of the novel SARS-CoV-2 virus has raised serious public health concerns due to the possibility of misdiagnosis in regions where arboviral diseases are endemic. We performed the first study in northern… read more here.
Keywords: chikv; sars cov; febrile patients; detection ... See more keywords
Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP.
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DOI: 10.1016/j.molcel.2020.04.013
Abstract: The primary interactions between incoming viral RNA genomes and host proteins are crucial to infection and immunity. Until now, the ability to study these events was lacking. We developed viral cross-linking and solid-phase purification (VIR-CLASP)… read more here.
Keywords: protein; protein interactions; chikv; chikv rna ... See more keywords