Chitinase 3-like 1 exacerbates cardiac dysfunction after myocardial infarction without alterations of neutrophil dynamics
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733084
Abstract: Objective: Clinical studies show that chitinase 3-like 1 (CHI3L1) plasma level is a strong predictor of all-cause of mortality in patients with heart failure. Studies from our lab revealed that CHI3L1 is elevated in hearts… read more here.
Keywords: chil1; physiology; dysfunction; chil1 chil1 ... See more keywords
Activated Neutrophils Secrete Chitinase-Like 1 and Attenuate Liver Inflammation by Inhibiting Pro-Inflammatory Macrophage Responses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.824385
Abstract: Excessive activation and recruitment of neutrophils are generally considered to be associated with pathological aggravation of multiple diseases. However, as the role of neutrophils in tissue injury repair is receiving increasing attention, it is necessary… read more here.
Keywords: chil1; activated neutrophils; liver inflammation; pro inflammatory ... See more keywords