Improved outcome of children with relapsed/refractory acute myeloid leukemia by addition of cladribine to re‐induction chemotherapy
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3681
Abstract: The preferred salvage treatment for children with relapsed/refractory acute myeloid leukemia (R/R‐AML) remains unclear. The combination of cladribine/Ara‐C/granulocyte‐colony stimulating factor and mitoxantrone (CLAG‐M) shown promising results in adult R/R‐AML. We aim to investigate the efficacy… read more here.
Keywords: relapsed refractory; children relapsed; refractory acute; myeloid leukemia ... See more keywords
Gemtuzumab ozogamicin in children with relapsed or refractory acute myeloid leukemia: a report by Berlin-Frankfurt-Münster study group
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DOI: 10.3324/haematol.2018.191841
Abstract: Despite intensified salvage treatments, children with relapsed/refractory acute myeloid leukemia (AML) have poor survival. We evaluated gemtuzumab ozogamicin (CD33-targeted drug) used on a compassionate basis in patients diagnosed from 1995 until 2014 within Acute Myeloid… read more here.
Keywords: myeloid leukemia; gemtuzumab ozogamicin; children relapsed; acute myeloid ... See more keywords
Use of blinatumomab and CAR T-cell therapy in children with relapsed/refractory leukemia: A case series study
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DOI: 10.3389/fped.2022.1100404
Abstract: Background The 5-year event-free survival rate for childhood acute lymphoblastic leukemia (ALL) has increased to more than 85%. However, the 5-year overall survival rate in children with relapsed/refractory ALL did not exceed 50%. In the… read more here.
Keywords: children relapsed; cell; refractory; relapsed refractory ... See more keywords