Vitamin C Deficiency and Oxidant Levels in Children With Transfusion-Dependent β-Thalassemia
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DOI: 10.1007/s13312-021-2257-8
Abstract: To study vitamin C levels in children with transfusion-dependent β-thalassemia and correlate with age, transfusions received and iron overload; and to study the effect of administering vitamin C on its levels and Malondialdehyde (MDA) in… read more here.
Keywords: transfusion dependent; vitamin levels; vitamin; deficiency ... See more keywords
Wrist Joint Skeletal Changes in Children With Transfusion-Dependent Thalassemia.
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DOI: 10.1097/bpo.0000000000001523
Abstract: BACKGROUND Arthropathies and bone deformities are well known to occur in patients with thalassemia major and have been attributed to the disease or to its therapy. Before the advent of chelation therapy, these children developed… read more here.
Keywords: therapy; transfusion dependent; thalassemia; dependent thalassemia ... See more keywords
Efficacy of Thalidomide Treatment in Children With Transfusion Dependent β-Thalassemia: A Retrospective Clinical Study
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DOI: 10.3389/fphar.2021.722502
Abstract: Background: Thalidomide has been reported as a promising treatment for reducing transfusion volume in adults with β-thalassemia. However, the evidence about the safety and efficacy of thalidomide on children with transfusion dependent β-thalassemia (TDT) is… read more here.
Keywords: efficacy thalidomide; treatment; transfusion; month treatment ... See more keywords
Link between Genotype and Multi-Organ Iron and Complications in Children with Transfusion-Dependent Thalassemia
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DOI: 10.3390/jpm12030400
Abstract: We evaluated the impact of the genotype on hepatic, pancreatic and myocardial iron content, and on hepatic, cardiac and endocrine complications in children with transfusion-dependent β-thalassemia (β-TDT). We considered 68 β-TDT patients (11.98 ± 3.67… read more here.
Keywords: iron; complications children; transfusion dependent; thalassemia ... See more keywords