Pharmacokinetics of isoniazid in children with tuberculosis—A comparative study at two doses
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DOI: 10.1002/ppul.24624
Abstract: To compare the pharmacokinetics of isoniazid (INH) at doses 5 and 10 mg/kg/day. read more here.
Keywords: comparative study; study two; children tuberculosis; isoniazid children ... See more keywords
Optimization of dosing regimens of isoniazid and rifampicin in children with tuberculosis in India
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DOI: 10.1111/bcp.13846
Abstract: Pharmacokinetic studies in the past have shown inadequate antituberculosis drug levels in children with the currently available dosing regimens. This study attempted to investigate the pharmacokinetics of isoniazid and rifampicin, when used in children, and… read more here.
Keywords: regimens isoniazid; dosing regimens; children tuberculosis; rifampicin children ... See more keywords
Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis
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DOI: 10.1371/journal.pone.0189101
Abstract: We measured hair and plasma concentrations of isoniazid among sixteen children with tuberculosis who underwent personal or video-assisted directly observed therapy and thus had 100% adherence. This study therefore defined typical isoniazid exposure parameters after… read more here.
Keywords: hair plasma; plasma area; exposure; children tuberculosis ... See more keywords