Strategies for designing proteolysis targeting chimaeras (PROTACs)
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DOI: 10.1002/med.21877
Abstract: Proteolysis targeting chimaeras (PROTACs) is a cutting edge and rapidly growing technique for new drug discovery and development. Currently, the largest challenge in the molecular design and drug development of PROTACs is efficient identification of… read more here.
Keywords: protacs; chimaeras protacs; proteolysis targeting; targeting chimaeras ... See more keywords
Proteolysis-targeting chimaeras (PROTACs) as pharmacological tools and therapeutic agents: advances and future challenges
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2022.2076675
Abstract: Abstract Proteolysis-targeting chimaeras (PROTACs) have been developed to be an emerging technology for targeted protein degradation and attracted the favour of academic institutions, large pharmaceutical enterprises, and biotechnology companies. The mechanism is based on the… read more here.
Keywords: protacs pharmacological; pharmacological tools; tools therapeutic; chimaeras protacs ... See more keywords