Bifunctional chimera for ligand-directed photo-degradation of oncogenic microRNA.
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DOI: 10.1039/d2cc06687d
Abstract: Targeted inhibition of oncogenic microRNAs provides a promising anti-cancer approach. Here, we report a bifunctional chimera for ligand-directed regulation of target oncogenic precursor microRNA through photo-degradation. Chimeric TGP-210-Ppa with photosensitizer pyropheophorbide a (Ppa) linked with… read more here.
Keywords: chimera; photo degradation; ligand directed; chimera ligand ... See more keywords