Development of Integrin Targeting Chimeras (ITACs) for the Lysosomal Degradation of Extracellular Proteins
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DOI: 10.1002/cmdc.202300643
Abstract: The emerging of lysosomal targeting chimera (LYTAC) expands the field of targeted protein degradation (TPD) to include the extracellular proteins for precise depletion. However, most of the reported LYTACs either induce ubiquitous degradation of the… read more here.
Keywords: extracellular proteins; degradation; integrin; targeting chimeras ... See more keywords