Advancements in Proteolysis Targeting Chimeras for Targeted Therapeutic Strategies in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Neurobiology"
DOI: 10.1007/s12035-025-04838-0
Abstract: The presence of hyperphosphorylated Tau proteins, which mislocalize and form neurofibrillary tangles, and the accumulation of amyloid-β plaques are hallmark features of Alzheimer’s disease (AD). These toxic protein aggregates contribute to synaptic impairment and neuronal… read more here.
Keywords: alzheimer disease; targeting chimeras; proteolysis targeting; chimeras targeted ... See more keywords