pH-Triggered Size-transformable and Bioactivity-switchable Self-assembling Chimeric Peptide Nano-assemblies for Combating Drug-Resistant Bacteria and Biofilms.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202210766
Abstract: Drug-resistant bacteria and biofilm-associated infections are prominent problems in the field of antibacterial medicine, seriously affecting human and animal health. Despite the great potential of nanomaterials in the antibacterial field, overcoming the paradox of size… read more here.
Keywords: chimeric peptide; peptide nano; self assembling; drug resistant ... See more keywords
A dual-usage near-infrared (NIR) cell membrane targeting chimeric peptide for cancer cell membrane imaging and photothermal ablation
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DOI: 10.1007/s10853-020-04546-1
Abstract: Due to the low background and deep tissue penetration of near-infrared light, near-infrared fluorescence (NIRF) probes have received much attention in recent years. Cell membrane targeting probes can be used in in vitro and in… read more here.
Keywords: chimeric peptide; cell membrane; near infrared; membrane targeting ... See more keywords
Enzyme-Driven Membrane-Targeted Chimeric Peptide for Enhanced Tumor Photodynamic-Immunotherapy.
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DOI: 10.1021/acsnano.9b04315
Abstract: Here, a protein farnesyltransferase (PFTase)-driven plasma membrane (PM)-targeted chimeric peptide PpIX-C6-PEG8-KKKKKKSKTKC-OMe (PCPK) was designed for PM-targeted photodynamic therapy (PM-PDT) and enhanced immunotherapy via tumor cell PM damage and fast release of damage-associated molecular patterns (DAMPs).… read more here.
Keywords: chimeric peptide; targeted chimeric; membrane targeted; membrane ... See more keywords
REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis
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DOI: 10.1371/journal.pone.0231240
Abstract: Objective REG-O3 is a 24-aminoacid chimeric peptide combining a sequence derived from growth hormone (GH) and an analog of somatostatin (SST), molecules displaying cartilage repair and anti-inflammatory properties, respectively. This study aimed to investigate the… read more here.
Keywords: chimeric peptide; osteoarthritis; joint function; function ... See more keywords