Designing of a Functional Chimeric Protein for Production of Nanobodies Against Human CD20: Molecular Dynamics Simulation and In Vitro Verification
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-018-9791-9
Abstract: One major issue in cancer immunotherapy is the large size of mAbs (150 kDa) which usually causes limitation in tumor penetration. Camel nanobodies ( read more here.
Keywords: protein; chimeric protein; molecular dynamics; dynamics simulation ... See more keywords
Synergy of bioinspired chimeric protein and silver nanoparticles for fabricating “kill-release” antibacterial coating
Sign Up to like & getrecommendations! Published in 2021 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2021.149799
Abstract: Abstract In view of the problem that medical materials are prone to contamination by bacteria that causing health threats, an antibacterial surface was designed by combining mussel-inspired chimeric protein with silver nanoparticles (AgNPs). The mussel-inspired… read more here.
Keywords: chimeric protein; kill release; protein silver; silver nanoparticles ... See more keywords
An approach to chimeric subunit immunogen provides efficient protection against toxicity, type III and type v secretion systems of Shigella.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108132
Abstract: OBJECTIVES Shigellosis is one of the infectious diseases causing severe intestinal illness in human beings. Development of an effective vaccine against Shigella is a key to deal with this bacterium. The present study aimed at… read more here.
Keywords: protection; chimeric protein; immunized mice; shigella ... See more keywords
A new triple chimeric protein as a high immunogenic antigen against anthrax toxins: theoretical and experimental analyses
Sign Up to like & getrecommendations! Published in 2019 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2018.1510419
Abstract: Abstract Background: Anthrax is a zoonotic disease caused by Bacillus anthracis and it can be deadly in 6 days. Considerable efforts have been conducted toward developing more effective veterinary and human anthrax vaccines because these… read more here.
Keywords: chimeric protein; high immunogenic; anthrax; antigen ... See more keywords
Chimeric Protein Designed by Genome-Scale Immunoinformatics Enhances Serodiagnosis of Bovine Neosporosis
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DOI: 10.1128/jcm.01343-19
Abstract: Neosporosis has become a concern since it is associated with abortion in cattle. Currently, in situ diagnosis is determined through anamnesis, evaluation of the history, and perception of the clinical signs of the herd. There… read more here.
Keywords: chimeric protein; immunoinformatic tools; bovine neosporosis; protein ... See more keywords
Selective Silencing of Disease-Associated B Lymphocytes from Hashimoto’s Thyroiditis Patients by Chimeric Protein Molecules
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315083
Abstract: Hashimoto’s thyroiditis is one of the most common endocrine disorders, affecting up to 20% of the adult population. No treatment or prevention exists except hormonal substitution for hypothyroidism. We hypothesize that it may be possible… read more here.
Keywords: cell; hashimoto thyroiditis; patients chimeric; chimeric protein ... See more keywords