Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners
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DOI: 10.1038/s41598-017-12214-9
Abstract: In eukaryotes, several “hub” proteins integrate signals from different interacting partners that bind through intrinsically disordered regions. The 14-3-3 protein hub, which plays wide-ranging roles in cellular processes, has been linked to numerous human disorders… read more here.
Keywords: proteins unraveling; chimeric proteins; disordered partners; unraveling interactions ... See more keywords
Installation of authentic BicA and SbtA proteins to the chloroplast envelope membrane is achieved by the proteolytic cleavage of chimeric proteins in Arabidopsis
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DOI: 10.1038/s41598-020-59190-1
Abstract: To improve the photosynthetic performance of C 3 plants, installing cyanobacterial bicarbonate transporters to the chloroplast inner envelope membrane (IEM) has been proposed for years. In our previous study, we successfully introduced chimeric cyanobacterial sodium-dependent… read more here.
Keywords: chloroplast iem; bica sbta; chimeric proteins; cleavage ... See more keywords
Chimeric proteins tagged with specific 3xHA cassettes may present instability and functional problems
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DOI: 10.1371/journal.pone.0183067
Abstract: Epitope-tagging of proteins has become a widespread technique for the analysis of protein function, protein interactions and protein localization among others. Tagging of genes by chromosomal integration of PCR amplified cassettes is a widely used… read more here.
Keywords: protein; proteins tagged; 3xha cassettes; tagged specific ... See more keywords
The Impact of the Antigenic Composition of Chimeric Proteins on Their Immunoprotective Activity against Chronic Toxoplasmosis in Mice
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DOI: 10.3390/vaccines7040154
Abstract: Toxoplasmosis may pose a serious threat for individuals with weakened or undeveloped immune systems. However, to date, there is no specific immunoprophylaxis for humans. Thus, the aim of this study was to evaluate the immunogenicity… read more here.
Keywords: chronic toxoplasmosis; antigenic composition; chimeric proteins; toxoplasmosis ... See more keywords