Scale up and pharmacokinetic study of a novel mutated chimeric tissue plasminogen activator (mt-PA) in rats
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DOI: 10.1038/srep43028
Abstract: Because of high mortality caused by cardiovascular diseases, various fibrinolytic agents with diverse pharmacokinetic and pharmacodynamic properties have been developed. A novel mutated chimeric tissue plasminogen activator (mt-PA) was developed by the removal of first… read more here.
Keywords: chimeric tissue; plasminogen; novel mutated; plasminogen activator ... See more keywords