A Single‐center, Open‐label, Parallel Control Study Comparing the Pharmacokinetics and Safety of a Single Oral Dose of Roflumilast and Its Active Metabolite Roflumilast N‐oxide in Healthy Chinese and Caucasian Volunteers
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DOI: 10.1002/cpdd.1209
Abstract: Roflumilast is a phosphodiesterase‐4 inhibitor which treats chronic obstructive pulmonary disease (COPD). Roflumilast N‐oxide is the major metabolite of roflumilast with a similar mechanism of action to roflumilast. Although racial differences in roflumilast drug disposition… read more here.
Keywords: roflumilast; chinese caucasian; roflumilast oxide; dose roflumilast ... See more keywords
Brain asymmetry differences between Chinese and Caucasian populations: a surface-based morphometric comparison study
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DOI: 10.1007/s11682-019-00184-7
Abstract: Asymmetry has been proved to exist in the human brain structure, function and behavior. Most of the existing brain asymmetry findings are originated from the western populations, while studies about the brain structural and functional… read more here.
Keywords: brain asymmetry; chinese caucasian; based morphometric; asymmetry ... See more keywords
Comparison of Pharmacokinetics of Aprepitant in Healthy Chinese and Caucasian Subjects
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DOI: 10.2147/dddt.s243924
Abstract: Purpose Aprepitant is used to prevent nausea and vomiting associated with moderately and highly emetogenic chemotherapy. In this open-label, 2-period study, the safety, tolerability, and pharmacokinetics (PK) of aprepitant (EMEND®) were evaluated in healthy Chinese… read more here.
Keywords: healthy chinese; caucasian subjects; period; pharmacokinetics aprepitant ... See more keywords
Corneal Biomechanics Differences Between Chinese and Caucasian Healthy Subjects
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DOI: 10.3389/fmed.2022.834663
Abstract: Purpose The aim of this study was to evaluate the difference between Caucasian and Chinese healthy subjects with regards to Corvis ST dynamic corneal response parameters (DCRs). Methods Two thousand eight hundred and eighty-nine healthy… read more here.
Keywords: caucasian healthy; chinese caucasian; corneal biomechanics; biomechanics differences ... See more keywords
Pancreas Fat, an Early Marker of Metabolic Risk? A Magnetic Resonance Study of Chinese and Caucasian Women: TOFI_Asia Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.819606
Abstract: Objective Prevalence of type 2 diabetes (T2D) is disproportionately higher in younger outwardly lean Asian Chinese compared to matched Caucasians. Susceptibility to T2D is hypothesised due to dysfunctional adipose tissue expansion resulting in adverse abdominal… read more here.
Keywords: asia study; chinese caucasian; risk; tofi asia ... See more keywords