Bioequivalence and Pharmacokinetic Profiles of 2 Trimetazidine Modified‐release Tablets Under Fasting and Fed Conditions in Chinese Healthy Subjects
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DOI: 10.1002/cpdd.1200
Abstract: This study aims to assess the bioequivalence of test and reference formulations of trimetazidine dihydrochloride in healthy Chinese volunteers under fasting and fed conditions, and to determine the effect of food on the pharmacokinetic profiles… read more here.
Keywords: fasting fed; fed conditions; profiles trimetazidine; bioequivalence ... See more keywords
The Pharmacokinetics and Bioequivalence of Desvenlafaxine Succinate in Chinese Healthy Subjects Under Fasting and Fed States.
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DOI: 10.1002/cpdd.1272
Abstract: Desvenlafaxine succinate is a selective serotonin-norepinephrine reuptake inhibitor for the treatment of major depressive disorder. The pharmacokinetic profile of desvenlafaxine succinate at the clinically recommended dose of 50 mg in Chinese healthy subjects has been reported… read more here.
Keywords: fasting fed; desvenlafaxine succinate; pharmacokinetics bioequivalence; chinese healthy ... See more keywords
Tolerance, variability, and pharmacokinetics of bevacizumab biosimilars in Chinese healthy male subjects
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DOI: 10.1007/s00280-018-3645-1
Abstract: ObjectiveThe aim of this study was to explore the tolerance, variability, and pharmacokinetics (PK) of bevacizumab biosimilars (MIL60, BAT1706, IBI305) in Chinese healthy male subjects.MethodsThis randomized, double-blind, two-arm, parallel studies included three separate investigations, which… read more here.
Keywords: bevacizumab biosimilars; chinese healthy; bevacizumab; pharmacokinetics bevacizumab ... See more keywords
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Sotagliflozin After Multiple Ascending Doses in Chinese Healthy Subjects
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DOI: 10.2147/dddt.s372575
Abstract: Background Sotagliflozin (LX4211) is a dual inhibitor of sodium-glucose cotransporter (SGLT)1 and SGLT2 being investigated to improve glycemic control in adults with diabetes. This study was firstly conducted to assess the pharmacokinetic (PK), pharmacodynamic (PD)… read more here.
Keywords: sotagliflozin; day; chinese healthy; safety tolerability ... See more keywords
Four-Week Supplementation of Water-Soluble Tomato Extract Attenuates Platelet Function in Chinese Healthy Middle-Aged and Older Individuals: A Randomized, Double-Blinded, and Crossover Clinical Trial
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.891241
Abstract: Background and Aims Platelets are linked to atherosclerotic development and pathological thrombosis. Single dose of water-soluble tomato extract (WTE) which is a natural extraction can exert anti-platelet effects after 3 or 7 h in British… read more here.
Keywords: supplementation; platelet; week; platelet function ... See more keywords
A Randomized, Double-Blind, Single-Dose Study Comparing the Biosimilarity of HOT-1010 With Bevacizumab (Avastin®) in Chinese Healthy Male Subjects
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.694375
Abstract: Objective: This study was conducted to compare the pharmacokinetics, safety and immunogenicity of HOT-1010 with bevacizumab (Avastin®) in Chinese healthy male subjects. Methods: A single-center, randomized, double-blind, single-dose, parallel trial was performed in 84 Chinese… read more here.
Keywords: healthy male; hot 1010; chinese healthy; bevacizumab avastin ... See more keywords
The Development of a Chinese Healthy Eating Index and Its Application in the General Population
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DOI: 10.3390/nu9090977
Abstract: The objective of this study was to develop a Chinese Healthy Eating Index (CHEI) based on the updated Dietary Guidelines for Chinese (DGC-2016) and to apply it in the 2011 China Health and Nutrition Survey… read more here.
Keywords: chinese healthy; index; chei; development chinese ... See more keywords