The genomic mutation spectrums of breast fibroadenomas in Chinese population by whole exome sequencing analysis
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2081
Abstract: Fibroadenomas (FAs) are the most common fibroepithelial lesions and the most common benign tumors of the breast in women of reproductive age. Although MED12 mutations, an overwhelming majority of all mutations, and some other gene… read more here.
Keywords: fas; genomic mutation; mutation spectrums; chinese population ... See more keywords
Prevalence of HPV‐16/18 genotypes and immediate histopathologic correlation results in a Chinese population with negative cytology and positive high‐risk HPV testing
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22180
Abstract: The objective of this study was to examine the prevalence of human papillomavirus 16/18 (HPV‐16/18) genotypes and immediate histopathologic correlations in a Chinese population with negative cytology and positive high‐risk human papillomavirus (hrHPV) testing. read more here.
Keywords: hpv genotypes; genotypes immediate; hpv; chinese population ... See more keywords
Genome-wide association studies combined with k-fold cross-validation identify rs17822931 as an ancestry-informative marker in Han Chinese population.
Sign Up to like & getrecommendations! Published in 2023 at "Electrophoresis"
DOI: 10.1002/elps.202200227
Abstract: DNA-based ancestry inference has long been a research hot spot in forensic science. The differentiation of Han Chinese population, such as the northern-to-southern substructure, would benefit forensic practice. In the present study, we enrolled participants… read more here.
Keywords: cross validation; chinese population; fold cross; han chinese ... See more keywords
Elevated neutrophil-to-lymphocyte ratio but not platelet-to-lymphocyte ratio is associated with generalized aggressive periodontitis in a Chinese population.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of periodontology"
DOI: 10.1002/jper.20-0282
Abstract: BACKGROUND Host inflammatory mediators are associated with tissue destruction in patients suffering from generalized aggressive periodontitis (GAgP). However, the correlations between neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with GAgP remain unknown. METHODS Periodontal clinical… read more here.
Keywords: chinese population; gagp; ratio; platelet lymphocyte ... See more keywords
Genetic testing of UGT1A1 in the diagnosis of Gilbert syndrome: The discovery of seven novel variants in the Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1958
Abstract: Genetic testing of UGT1A1 was used to facilitate the diagnosis of Gilbert syndrome, and analyze the distribution features of pathogenic variants in the Chinese population. read more here.
Keywords: variants chinese; diagnosis gilbert; genetic testing; chinese population ... See more keywords
Genetic polymorphisms and mutation rates of 16 X-STRs in a Han Chinese population of Beijing and application examples in second-degree kinship cases
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-019-02047-8
Abstract: As a supplementary tool in forensic cases, X chromosomal short tandem repeats (X-STRs) might bridge large pedigree gaps and bring inspiration to forensic practices for the special mode of inheritance. To standardize the application of… read more here.
Keywords: population beijing; han chinese; chinese population; population ... See more keywords
SNCA but not DNM3 and GAK modifies age at onset of LRRK2-related Parkinson’s disease in Chinese population
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09336-7
Abstract: BackgroundRecently, rs2421947 in DNM3 (dynamin 3) was reported as a genetic modifier of age at onset (AAO) of LRRK2 G2019S-related Parkinson’s disease (PD) in a genome-wide association study in Arab-Berber population. Rs356219 in SNCA (α-synuclein)… read more here.
Keywords: snca; dnm3; chinese population; lrrk2 related ... See more keywords
Association of CXCR2 genotype variations with HCV clearance in a Chinese population
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Virology"
DOI: 10.1007/s00705-018-3872-0
Abstract: Chemokines are known to play a vital role in guiding and regulating the immune response to viral infections. The chemokine CXC subfamily is a major subfamily in the chemokine family. Outcomes of hepatitis C virus… read more here.
Keywords: cxcr2 rs1126579; response; chinese population;
An eQTL variant of ALDH1A2 is associated with Kashin-Beck disease in Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-021-01287-2
Abstract: The aims of the study were to investigate the relationship between aldehyde dehydrogenase 1 family member A2 (ALDH1A2) and Kashin-Beck disease (KBD), explore the effects of the rs3204689 polymorphism and methylation status on the expression… read more here.
Keywords: aldh1a2 associated; chinese population; kashin beck; beck disease ... See more keywords
CDC25B is associated with the risk of hepatocellular carcinoma, but not related to persistent infection of hepatitis B virus in a Chinese population
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05408-4
Abstract: The cell division cycle 25 (CDC25) gene members, including CDC25A, CDC25B and CDC25C, are reported to be associated with several human cancers. Here, we aim to investigate the association of functional polymorphisms of CDC25 gene… read more here.
Keywords: risk; infection; hbv; chinese population ... See more keywords
Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-018-0323-6
Abstract: Antipsychotic-induced weight gain (AIWG) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. We aimed to review the progress of pharmacogenetic studies… read more here.
Keywords: antipsychotic induced; induced weight; aiwg chinese; chinese population ... See more keywords