TET2-Driven Clonal Hematopoiesis and Response to Canakinumab: An Exploratory Analysis of the CANTOS Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.0386
Abstract: Importance Clonal hematopoiesis of indeterminate potential (CHIP) is associated with increased risk of atherosclerotic cardiovascular disease, and mouse experiments suggest that CHIP related to Tet2 loss of function in myeloid cells accelerates atherosclerosis via augmented… read more here.
Keywords: trial; randomized clinical; clinical trial; chip ... See more keywords
Rapid Prototyping of Ultralow‐Cost, Inkjet‐Printed Carbon Microelectrodes for Flexible Bioelectronic Devices
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700136
Abstract: Gaining better understanding of the human brain using chip‐based devices and promoting the recovery of lost biological functionality through implants are long pursued endeavors driven by advances in material science, bioelectronics, and the advancing silicon… read more here.
Keywords: printed carbon; carbon; rapid prototyping; prototyping ultralow ... See more keywords
Mimicking Human Pathophysiology in Organ‐on‐Chip Devices
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201800109
Abstract: Convergence of life sciences, engineering, and basic sciences has opened new horizons for biologically inspired innovations, and a considerable number of organ‐on‐a‐chip platforms have been developed for mimicking physiological systems of biological organs such as… read more here.
Keywords: chip platforms; mimicking human; organ chip; disease ... See more keywords
Autonomous Integrated Microfluidic Circuits for Chip‐Level Flow Control Utilizing Chemofluidic Transistors
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201700430
Abstract: In microfluidics, a variety of platforms have emerged facilitating various physical effects for manipulating small volumes. Despite great functional diversity, most technologies are incapable of acting on direct feedback from the process liquid and instead… read more here.
Keywords: control; integrated microfluidic; autonomous integrated; chip level ... See more keywords
Self‐Adaptive All‐In‐One Delivery Chip for Rapid Skin Nerves Regeneration by Endogenous Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202001751
Abstract: Skin wound therapy aims not only to restore skin protection but also to recover excitation functions through nerve regeneration. During the restoration of skin nerves, the recruitment of endogenous stem cells and promotion of neuronal… read more here.
Keywords: self adaptive; delivery; stem cells; chip ... See more keywords
Hybrid Chalcogenide‐Germanosilicate Waveguides for High Performance Stimulated Brillouin Scattering Applications
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202105230
Abstract: On‐chip stimulated Brillouin scattering (SBS) in arsenic trisulfide (As2S3) planar waveguides lead to a range of outstanding demonstrations in microwave photonics signal generation and processing. However, the lack of other integrated functionalities, high back reflections,… read more here.
Keywords: stimulated brillouin; brillouin scattering; hybrid chalcogenide; chalcogenide germanosilicate ... See more keywords
High-throughput on-chip human mesenchymal stromal cell potency prediction.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101995
Abstract: Human mesenchymal stromal cells (hMSCs) are a promising source for regenerative cell therapy. However, hMSC clinical use has been stymied by product variability across hMSC donors and manufacturing practices resulting in inconsistent clinical outcomes. The… read more here.
Keywords: mesenchymal stromal; human mesenchymal; potency; high throughput ... See more keywords
Quenching Epigenetic Drug Resistance Using Anti-hypoxic Microparticles in Glioblastoma Patient-derived Chips.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202102226
Abstract: Glioblastoma is one of the most intractable tumor types due to the progressive drug resistance upon tumor mass expansion. Incremental hypoxia inside the growing tumor mass drives epigenetic drug resistance by activating non-genetic repair of… read more here.
Keywords: drug; drug resistance; chip; epigenetic drug ... See more keywords
Micropathological Chip Modeling the Neurovascular Unit Response to Inflammatory Bone Condition
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102305
Abstract: Organ‐on‐a‐chip in vitro platforms accurately mimic complex microenvironments offering the ability to recapitulate and dissect mechanisms of physiological and pathological settings, revealing their major importance to develop new therapeutic targets. Bone diseases, such as osteoarthritis,… read more here.
Keywords: innervation; bone; micropathological chip; inflammatory bone ... See more keywords
Thyroid‐on‐a‐Chip: An Organoid Platform for In Vitro Assessment of Endocrine Disruption
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201555
Abstract: Thyroid is a glandular tissue in the human body in which the function can be severely affected by endocrine disrupting chemicals (EDCs). Current in vitro assays to test endocrine disruption by chemical compounds are largely… read more here.
Keywords: vitro; chip; endocrine disruption; thyroid chip ... See more keywords
Cell Membranes from Tumor-tropic MSCs Screened by a Microfluidic Chip for Drug Nanoparticles Encapsulation and Cancer Targeted Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202904
Abstract: Nanoparticles (NPs)-based drug carriers are effective in reducing systemic toxicity and drug resistance for chemotherapy, and an emerging trend focuses on integrating cell membranes with nanomedicines for tumor targeting. Mesenchymal stem cells (MSCs) are promising… read more here.
Keywords: cell membranes; cell; chip; drug ... See more keywords