A microfluidic lung-on-a-chip based on biomimetic hydrogel membrane.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.28426
Abstract: Lung-on-chips have showed great promise as a tool to recapitulate the respiratory system for investigation of lung diseases in the past decade. However, the commonly applied artificial elastic membrane (e.g., polydimethylsiloxane, PDMS) in the chip… read more here.
Keywords: chip based; lung; lung chip; membrane ... See more keywords
Rapid Fabrication of Chip‐Based Physiometers for Neurobehavioral Toxicity Assays Using Rotifers Brachionus calyciflorus
Sign Up to like & getrecommendations! Published in 2018 at "Cytometry Part A"
DOI: 10.1002/cyto.a.23510
Abstract: An increased interest in implementations of Lab‐on‐a‐Chip (LOC) technologies for in‐situ analysis of multicellular metazoan model organisms and their embryonic stages demands development of new prototyping techniques. Due to size of multicellular organisms the fabrication… read more here.
Keywords: brachionus calyciflorus; chip based; microscopy; rotifers brachionus ... See more keywords
Rapid multi‐attribute characterization of intact bispecific antibodies by a microfluidic chip‐based integrated icIEF‐MS technology
Sign Up to like & getrecommendations! Published in 2022 at "Electrophoresis"
DOI: 10.1002/elps.202200165
Abstract: Rapid, direct identification and quantitation of protein charge variants, and assessment of critical quality attributes with high sensitivity are important drivers required to accelerate the development of biotherapeutics. We describe the use of an enhanced… read more here.
Keywords: chip based; microfluidic chip; charge variants; charge ... See more keywords
A point‐of‐care diagnostic system to influenza viruses using chip‐based ultra‐fast PCR
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25046
Abstract: In order to diagnose the infectious disease from clinical samples, the various protocols such as culturing microorganism, rapid diagnostic test using chromatographic method, ELISA, conventional PCR are developed. Since a novel strain of avian influenza… read more here.
Keywords: pcr; point care; influenza; chip based ... See more keywords
Organ/body-on-a-chip based on microfluidic technology for drug discovery.
Sign Up to like & getrecommendations! Published in 2018 at "Drug metabolism and pharmacokinetics"
DOI: 10.1016/j.dmpk.2017.11.003
Abstract: Although animal experiments are indispensable for preclinical screening in the drug discovery process, various issues such as ethical considerations and species differences remain. To solve these issues, cell-based assays using human-derived cells have been actively… read more here.
Keywords: chip based; drug; drug discovery; body chip ... See more keywords
Routing design in optical networks-on-chip based on gray code for optical loss reduction
Sign Up to like & getrecommendations! Published in 2021 at "Optik"
DOI: 10.1016/j.ijleo.2020.166198
Abstract: Abstract An advanced electronics world and enhanced capability in nanoscale circuitry design require optimal integration in the design of electronic systems. Efforts are still being made to design and build integrated systems. In the old… read more here.
Keywords: chip based; optical loss; networks chip; chip ... See more keywords
Plasma epidermal growth factor receptor mutation testing with a chip-based digital PCR system in patients with advanced non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Lung cancer"
DOI: 10.1016/j.lungcan.2017.02.001
Abstract: OBJECTIVES Epidermal growth factor receptor (EGFR) mutation testing is a companion diagnostic to determine eligibility for treatment with EGFR tyrosine kinase inhibitors (EGFR-TKIs) in non-small cell lung cancer (NSCLC). Recently, plasma-based EGFR testing by digital… read more here.
Keywords: chip based; treatment; mutation; lung cancer ... See more keywords
Synthesis and photoluminescence properties of Eu2+ activated CaO ceramic powders for near-ultraviolet chip based white light emitting diodes
Sign Up to like & getrecommendations! Published in 2017 at "Optical Materials"
DOI: 10.1016/j.optmat.2017.03.051
Abstract: Abstract In this paper, we synthesized series of Eu 2+ activated CaO ceramic powders by conventional solid state reaction. Using NH 4 Cl as a reducing additives, the Eu 3+ has been successfully reduced to… read more here.
Keywords: chip based; cao ceramic; activated cao; near ultraviolet ... See more keywords
Highly Accurate Chip-Based Resequencing of SARS-CoV-2 Clinical Samples
Sign Up to like & getrecommendations! Published in 2021 at "Langmuir"
DOI: 10.1021/acs.langmuir.0c02927
Abstract: SARS-CoV-2 has infected over 128 million people worldwide, and until a vaccine is developed and widely disseminated, vigilant testing and contact tracing are the most effective ways to slow the spread of COVID-19. Typical clinical… read more here.
Keywords: chip based; accurate chip; highly accurate; sars cov ... See more keywords
Chip-based quantum key distribution
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms13984
Abstract: Improvement in secure transmission of information is an urgent need for governments, corporations and individuals. Quantum key distribution (QKD) promises security based on the laws of physics and has rapidly grown from proof-of-concept to robust… read more here.
Keywords: chip based; key distribution; quantum key; based quantum ... See more keywords
Repeated dose multi-drug testing using a microfluidic chip-based coculture of human liver and kidney proximal tubules equivalents
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65817-0
Abstract: A microfluidic multi-organ chip emulates the tissue culture microenvironment, enables interconnection of organ equivalents and overcomes interspecies differences, making this technology a promising and powerful tool for preclinical drug screening. In this study, we established… read more here.
Keywords: microfluidic chip; chip based; liver; drug ... See more keywords